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Effects of the resistance exercise on muscle and vascular function in older adults with reduction of muscle strength and mass.

Effects of a low-intensity resistance exercise program with vascular occlusion on muscle function and microcirculation in older people with Sarcopenia

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6cywff
Enrollment
Unknown
Registered
2020-01-06
Start date
2014-02-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcopenia

Interventions

The subjects will be divided into 3 groups as follows: a) group 1 (20 older adults) - exercise intensity set at 30 % of a maximum repetition with blood flow restriction
b) group 2 (20 older adults) - exercise intensity set at 30 % of a maximum repetition without blood flow restriction
c) group 3 (20 older adults) - exercise intensity set at 70 % of a maximum repetition without blood flow restriction. The subjects will perform the sequence of four resistance exercises, two for uppe
Other
E07.858.690.930

Sponsors

Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ)
Lead Sponsor
Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ)
Collaborator

Eligibility

Age
65 Years to 100 Years

Inclusion criteria

Inclusion criteria: Age 65 to 100 years without regular physical activity for at least six months with sarcopenia.

Exclusion criteria

Exclusion criteria: Muscle problems; cardiovascular diseases; obesity; smoking; cancer; diabetes mellitus; autoimmune diseases.

Design outcomes

Primary

MeasureTime frame
Increase of muscle mass by dual x-ray Absorptiometry;Increase of muscle strength by handgrip and isokinetic dynamometer;Increase of vascular reactivity by venous occlusion plethysmography and videocapilaroscopy;Increase of cardiac autonomic modulation by heart rate variability;Decrease of inflammation and oxidative stress by blood biochemistry—

Secondary

MeasureTime frame
No secondary outcomes expected—

Countries

Brazil

Contacts

Public ContactKarynne Lopes

Laboratório de Atividade Física e Promoção da Saúde (LABSAU) do Instituto de Educação Física e Desportos da Universidade do Estado do Rio de Janeiro (UERJ)

kjgolrj@gmail.com+550212334-0775

Outcome results

None listed

Source: REBEC (via WHO ICTRP)