Osteopenia, Osteoporosis, postmenopausal women
Conditions
Interventions
52 volunteers were distributed into three groups, according to randomly parallel form: Resistance Training 3times-per-week (RT 3/week, n=20)
Resistance Training 2times-per-week (RT 2/week, n=16) and control group (CG, n=16). The following assessment tools were used: bone mineral density (BMD) by dual X-ray absorptiometry, ‘Latin America Gr
Drug
Procedure/surgery
F01.145.632
Sponsors
Universidade Federal do Estado do Rio de Janeiro (UNIRIO)
Universidade do Estado do Pará (UEPA)
Eligibility
Sex/Gender
Female
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: Female volunteers; aged over or equal 50 years; with low BMD (T – score < -1DP); different ethnic population (descendants of Europeans, Blacks and Indians); patients being treated with sodium alendronate (70 mg) and/or vitamin D3; postmenopausal women (menopause of age self-declared); no previous history of fractures; no regular practice of physical activity for at least 1 year; with indication / medical clearance for physical exercises practices.
Exclusion criteria
Exclusion criteria: Who made some kind of surgical procedure in the last six months; who had early menopause by ovary removal; with uncontrolled hyperteho made some sort of surgery in the last snsion; that use additional bone active medications or hormone replacement therapy and volunteers who were being treated with drugs that induces low BMD, as glucocorticoids; volunteers with excessive use for alcohol and tobacco; that were not available to participate in all stages of the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome variable was the bone mineral density (BMD). The objective was to investigate the effect of different programs of resistance exercises of thirteen months on BMD in postmenopausal women with low BMD. The BMD was evaluated by dual-energy X-ray absorptiometry(DXA). After the study period were expected to a difference (p 0,05) between groups. The results in mean valuers of pre-test Neck femur for groups: TR3, n=20 (BMD neck Femur= 0.768 g/cm²);TR2, n=16 (BMD neck Femur=0.790 g/cm²)e GC, n=16 (BMD neck Femur=0.786). No estatistical differences (p>0,05) between groups. The results in mean valuers of pre-test trochanter for groups: TR3, n=20 (BMD Trochanter=0.678 g/cm²);TR2, n=16 (BMD Trochanter=0.697 g/cm²)e GC, n=16 (BMD Trochanter=0.696). No estatistical differences (p>0,05) between groups. The results in mean valuers of pre-test total femur for groups: TR3, n=20 (BMD total femur=0.714 g/cm²);TR2, n=16 (BMD total femur=0.738 g/cm²)e GC, n=16 (BMD total femur=0.732). No estatistical differences (p>0,05) between groups. ;The primary endpoint for DMD (pre and post-tests) by dual-energy X-ray absorptiometry(DXA): The results for bone mineral density (BMD) in percentage (%) valuers and p-valuer, shows that RT3/week presented intra-group improvements for all bone variables, as follows: L2-L4 (%=0.07%, p=0.023); neck femur (%=0.12%, p=0.001), trochanter (%=0.09%, p=0.0001), total femur (%=0.12%, p=0.0001), total BMD (%=0.10%, p=0.0001). And again, the RT3/week showed better results (p<0.05) compared to CG for BMD variables: Neck femur (%=0.12%, p=0.003), trochanter (%=0.08%, p=0.006); total femur (%=0.10%, p=0.0001), total BMD (%=0.09%, p=0.001). In addition, the RT2/week was statistically better compared with CG in total BMD (%=0.06%, p=0.046). And, the CG remained with stable BMD. | — |
Secondary
| Measure | Time frame |
|---|---|
| The outcome variable was Functional Autonomy. The objective was to investigate the effect of different programs of resistance exercises of thirteen months on the functional autonomy in postmenopausal women with low BMD. The functional autonomy index (IG) was evaluated by GDLAM protocol. After the study period were expected to a difference (p 0,05). No estatistical differences (p>0,05). ;The endpoint for functional autonomy (pre and post-tests) by GDLAM protocol: The results for Autonomy Index (AI) GDLAM protocol in % valuers and p-valuers, showed that both experimental groups were effective (intra-group p0,05). ;The endpoint for quality of life (pre and post-tests) by OPAQ: For quality of life total points (total score-OPAQ) was used. The experimental groups showed improvement (p0,05). ;The endpoint for muscular strength (pre and post-tests) by 10RM test: The results for strength (10 RM) in % valuers and p-valuers, also showed that both experimental groups were effective (intra-groups) for Leg Press 45°: RT3/week (%=78.85%, p<0.0001) and RT2/week (%=62.31%, p<0.0001). The RT3/week also showed better results (%=24.97%, p=0.001) compared with RT2/week. Also, both experimental groups: RT3/week (%=84.1%, p<0.0001) and RT2/week (%=59.1%, p<0.0001) showed better results compared with CG. The results for knee extension, again for both experimental groups were effective (intra-groups): RT3/week (%=15.5%, p<0.0001) and RT2/week (%=18.8%, p<0.0001). Also, the RT3/week (%=15.28%, p<0.0001) and RT2/week (% = 20.37%, p<0.0001) were also better compared to the CG. | — |
Countries
Brazil
Contacts
Public ContactEstélio Dantas
Universidade Federal do Estado do Rio de Janeiro (UNIRIO)
Outcome results
None listed