Skip to content

Laser to control bacteria that cause caries

Evaluation of Antimicrobial Photodynamic Therapy in the control of bacterial dental biofilm in children

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-6bqfp3
Enrollment
Unknown
Registered
2020-03-02
Start date
2018-02-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pathological conditions, signs and symptoms Dental Plaque Products with Antimicrobial Action

Interventions

The 25 volunteer patients participated in the research only once, and there is no need to repeat the procedure. The biofilm was collected from the region close to the gingiva of the lower molar teeth
Other
E02.594.540

Sponsors

Universidade de São Paulo
Lead Sponsor
Universidade de São Paulo
Collaborator

Eligibility

Age
6 Years to 12 Years

Inclusion criteria

Inclusion criteria: High risk for caries disease. Presence of teeth 36 and 46 completely erupted and with the buccal and lingual surfaces intact

Exclusion criteria

Exclusion criteria: Low or medium risk for caries disease. Spontaneous pain. Fistula. Caries lesion involving dentin. Systemic diseases. Antibiotic use in the last six months prior to the survey. Use of mouthwashes with auxiliary chemical substances to control biofilm and / or caries. Use of orthodontic appliances or prostheses. Dye sensitivity

Design outcomes

Primary

MeasureTime frame
Best antimicrobial action of photodynamic therapy with pre-irradiation time of 5 minutes, in dental biofilm, observed by the formation of bacterial colony forming units when compared to the pre-irradiation time of 01 minutes;It was proved after statistical analysis that the two pre-irradiation times, 01 minutes and 05 minutes, presented similar results, but the time of 05 minutes showed greater effectiveness, albeit discrete.

Secondary

MeasureTime frame
Secondary outcomes are not expected

Countries

Brazil

Contacts

Public ContactNicole ;Nicole Lima;Lima

Universidade de São Paulo;Universidade de São Paulo

nicole_gl@hotmail.com;nicole_gl@hotmail.com+5511943542030;+5511943542030

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 17, 2026