Dental Caries
Conditions
Interventions
daily use of 0.06 per cent chlorhexidine mouthwash
use of toothpaste with high fluoride concentration (5,000 ppm)
This is a randomized controlled open clinical trial with paralell arms. The study will include 120 adults of both sexes, with severe or morbid obesity with surgical indication (BMI higher or equal 35
topical application of fluoride varnish. All groups will receive the same oral hygiene kits, with the same type of toothbrush and floss for all groups to control confounding factors. With the exceptio
use of dental floss 1 time per day
and educational program (Freitas et al., 2017)
2. Chlorhexidine 0.06 per cent: daily use 2 times per day (Zimmer et al., 2015
James et al., 2017) for 3 months, with the possibility of extension up to 6 months
Toothpaste with high fluoride concentration (5,000 ppm): three brushings per day, twice with toothpaste with 5,000 ppm fluoride (Nordstrom and Birkhed, 2010
Manaa et al., 2014
Fernandez et al., 2017
Vale et al. ., 2022)
Topical application of fluoride varnish: top
D02.078.370.141.100
Sponsors
Universidade Federal de São Paulo (UNIFESP)
Universidade Federal de São Paulo (UNIFESP)
Eligibility
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Adults. Both sexes. Severe or morbid obesity with surgical indication (body mass index higher or equal 35 kg/m2)
Exclusion criteria
Exclusion criteria: Chronic diseases other than obesity such as cancer, arthritis, asthma, neurological or neurodegenerative diseases. Chronic use of systemic or oral medications that interfere with salivary flow. Smoking. Alcoholism. Use of illicit drugs. Oro-dentofacial diseases. Facial/dental Trauma. Extensive tooth loss. Active carious lesions. Periodontal pockets larger than 3 mm
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to evaluate the incidence of caries and periodontal disease using oral clinical indices, comparing the indices at baseline, 3 and 6 months after bariatric surgery and between the four treatment groups | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondarily, we hope to evaluate the impact of therapeutic measures on the oral microbiota and salivary markers at 3 and 6 months after surgery | — |
Countries
Brazil
Contacts
Public ContactPaula Castelo Ferrua
Universidade Federal de São Paulo- UNIFESP
Outcome results
None listed