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Effect of aged garlic extract on cardiovascular health: a randomized 12-week placebo-controlled study

The effect of aged garlic extract on the blood pressure of hypertensive patients and their relationship to the nutritional status of vitamins b6, b9 and b12

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
REBEC
Registry ID
RBR-69c4qq
Enrollment
Unknown
Registered
2019-06-03
Start date
2019-04-20
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hypertension

Interventions

The experimental group will consist of 25 participants diagnosed with hypertension who will be instructed to take 4 tablets of Aged Garlic Extract per day for 12 weeks. Participants will be advised to
Dietary supplement
B01.650.940.800.575.912.250.618.100.050.060.300
D26.660

Sponsors

Universidade Federal de Sergipe
Lead Sponsor
Universidade Federal de Sergipe
Collaborator

Eligibility

Age
20 Years to 59 Years

Inclusion criteria

Inclusion criteria: Arterial hypertension

Exclusion criteria

Exclusion criteria: Psychiatric disorder; allergy to garlic and sulfur; terminal illness; anemia; infection; pregnancy; use of multivitamin or garlic supplement in the last 6 months; can not give informed consent; are participating in another clinical trialand and malnutrition

Design outcomes

Primary

MeasureTime frame
Expected outcome 1: blood pressure control, ie, reduction of blood pressure in patients who received the garlic extract aged in relation to those who will receive the placebo.;Expected outcome 2: the hypotensive effect of the aged garlic extract will occur in patients with adequate nutritional status of vitamins B6, B9 and B12.

Secondary

MeasureTime frame
Reduction of cardiovascular markers: blood lipids, such as HDL-c, LDL-c, and total cholesterol Reduced fasting blood glucose. Reduction of anthropometric measures: Percentage of fat and waist circumference

Countries

Brazil

Contacts

Public ContactKiriaque Barbosa

Universidade Federal de Sergipe

kiribarra@yahoo.com.br+55-079-998361958

Outcome results

None listed

Source: REBEC (via WHO ICTRP)