Prostatic neoplasms Neoplasms
Conditions
Interventions
This is a randomized, controlled, two-arm, open-label clinical trial with sixty men divided into three intervention groups for fourteen weeks with the first week for baseline tests followed by twelve
Sponsors
Hospital Universitário Pedro Ernesto da Universidade do Estado do Rio de Janeiro
Hospital Universitário Pedro Ernesto da Universidade do Estado do Rio de Janeiro
Eligibility
Sex/Gender
Male
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: age between forty and sixty years; individuals with localized low-risk or very low-risk, non-aggressive prostate cancer; individuals under active surveillance as primary treatment for at least three months and with no plans for radical treatments at the time of recruitment; prostate-specific antigen less than or equal to ten and Gleason score less than or equal to six; no previous treatment for prostate cancer; life expectancy greater than five years; medical clearance for physical training.
Exclusion criteria
Exclusion criteria: existence of limiting musculoskeletal problems in the execution of the proposed exercises; existence of symptomatic and or uncontrolled cardiovascular diseases; not having been treated for any other type of cancer in the five years prior to data collection; metastasis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| improvements in physical fitness indicators are expected, verified by cardiopulmonary exercise test for cardiorespiratory fitness, isokinetic dynamometry for muscle strength and dual-energy x-ray absorptiometry (dexa) for body composition, observing the evolution of indices between the first and last week | — |
Secondary
| Measure | Time frame |
|---|---|
| improvement or maintenance of prostate-specific antigen (psa) levels is expected, verified through blood laboratory tests, comparing measurements collected in the pre and post fourteen-week intervention period;a reduction in the inflammatory markers interleukin-6 (il-6), tumor necrosis factor (tnf-alpha) and c-reactive protein is expected to be observed, verified by blood biochemical analysis method, from the comparison of baseline and final data;positive effects on the pleasure perceived by individuals are expected to be found, verified through the application of the physical activity enjoyment scale (paces), analyzed throughout the training weeks | — |
Countries
BR
Contacts
Public ContactWalace Monteiro
Universidade do Estado do Rio de Janeiro - UERJ
Outcome results
None listed