Urinary Bladder Neoplasms
Conditions
Interventions
Intervention - 50 patients submitted to Holmium Laser Enucleation of Bladder tumors (HoLEBT) and morcellation
Controle - 50 patients submitted to Transurethral Ressection of Bladder Tumors (TURBT)
Sponsors
Universidade de Sao Paulo - Instituto do Câncer do Estado de São Paulo (ICESP)
Universidade de Sao Paulo - Instituto do Câncer do Estado de São Paulo (ICESP)
Eligibility
Age
18 Years to 90 Years
Inclusion criteria
Inclusion criteria: Volunteers with tumors larger than 3 cm; older than 18 years; able to understand and willing to sign a written informed consent; satisfactory clinical pre operators conditions for surgery
Exclusion criteria
Exclusion criteria: Previous diagnosis of mibc; turbt in the last 5 years; radiological or clinical features of mibc; urethral stenosis; previous intravesical or systemic chemotherapy; previous use of bcg; no clinical conditions for surgery
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Assess the presence of detrusor muscle in the specimen | — |
Secondary
| Measure | Time frame |
|---|---|
| Assess the rate of recurrence or progression at 3, 6, 9, 12, 15, 18 and 24 months; We will observe the rates of bleeding, perforation, hyponatremia and complete resection at the end of the surgery ;Length of hospital stay, total time of irrigation, clot retention, UTI and other complications after surgery (Clavien-Dindo);To assess the presence of residual tumor in the re-TUR with 30 days | — |
Countries
Brazil
Contacts
Public ContactAlexandre Iscaife
Universidade de Sao Paulo - Instituto do Câncer do Estado de São Paulo (ICESP)
Outcome results
None listed