Carbohydrate metabolism. Insulin resistance.
Conditions
Interventions
Patients with gynecological surgery scheduled for a period of 6 months (approximately 30 in each group) will be invited to participate in the research, after pre-anesthetic release for the procedure,
Dietary supplement
SP6.051.227
Sponsors
Universidade Federal de São Paulo
Universidade Federal de São Paulo
Eligibility
Sex/Gender
Female
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: women; age between 18 and 70; body mass index less than 40 kg/m2; have a pre-anesthetic evaluation with a classification without surgical risk taking into consideration the classification of the American Association of Anesthesiology.
Exclusion criteria
Exclusion criteria: patients with gastrointestinal, respiratory, C-reactive protein levels greater than 6mg/dL; time of surgery greater than 4 hours, use of steroids for more than 6 months before surgery.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Presentation of the expected outcome- the abbreviation of preoperative fasting with carbohydrate-enriched liquid and protein may decrease insulin resistance; (HOMA index), with a decrease of at least 5% of that index in the group with carbohydrate and protein solution ingestion compared to the control group in the pre and post-intervention measurements.;Presentation of the Outcome found- the coefficient of variation of the median difference in blood glucose (55.19%), insulin (30.73%), albumin (2.33%) and HOMA (17.27%), between pre- and postoperative (32.53%), insulin (22.3%), albumin (0.91%), and HOMA (8%) were significantly higher in the control groups than in the control groups. , 46%) between the pre and postoperative phases of the juice group. There was a more than half decrease in insulin resistance in the group with carbohydrate and protein solution ingestion compared to the control in the pre and post-intervention measurements. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary outcomes are not expected | — |
Countries
Brazil
Contacts
Public ContactGisele Marquini
Universidade Federal de São Paulo
Outcome results
None listed