Knee osteoarthritis
Conditions
Interventions
The protocol group in the on-site circuit (control group) will be composed of 50 participants of both sexes, aged 40 years or older and diagnosed with osteoarthritis grades 2 and 3. The in-circuit pro
Sponsors
Universidade Federal de São Carlos
Universidade Federal de São Carlos
Eligibility
Age
40 Years to No maximum
Inclusion criteria
Inclusion criteria: Participants of both sexes, aged 40 years or older and diagnosed radiographically and clinically with unilateral or bilateral knee OA, grade II or III, according to the criteria of Kellgren and Lawrence, 1957, and American College of Rheumatology. For participants who present bilateral knee OA, the most symptomatic side will be used for evaluation.
Exclusion criteria
Exclusion criteria: Individuals who undergo physical therapy or any type of physical activity regularly up to 6 months prior to the start of the evaluation of this study and individuals who have had previous knee surgery, use of infiltration of corticosteroids in the knees, and have history of lower limb trauma within 30 days prior to evaluation. Also excluded are individuals who use prosthesis partial or total of hip or knee, and use of chondroprotectors, or are carriers of rheumatic diseases, and cognitive deficit that compromises the understanding of the tests. Individuals with a body mass index, BMI, greater than 30 kg by m2, uncontrolled heart disease, a history of severe muscle injuries above grade I, motor deficits due to neuromuscular disease or any other medical restriction that makes it impossible to participate in this study, will also be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain intensity will be measured using the Visual Analogue Scale (VAS). This is a reliable measure of pain that consists of a 100 mm line on which the participants should mark between the left side (0, representing “no pain”) and 100 (representing “the worst pain imaginable”). This measure will be self-reported on a paper form. The minimum clinically important difference (MCID) of 17.5 mm from the 100 mm VAS will be considered to verify clinical improvement between the pre and post-intervention moments.;To assess physical function, the Western Ontario and McMaster Universities (WOMAC) questionnaire will be used, a self-administered instrument that addresses the impact and restrictions on quality of life, specifically for patients with lower limb OA. The questionnaire has been translated into Portuguese and validated, consisting of 24 questions divided into three domains: pain, stiffness and physical function. The physical function subscale contains 17 questions, and the score is made using a Likert scale, whereby each question is scored between “no dysfunction” (score = 0) to “extreme dysfunction” (score = 4). Total score ranges from 0 to 68, with higher scores indicating worse function. Self-reported answers will be registered on a paper form. For change in WOMAC function sub-scale, the MCID of 12% (8.16 from 0-68) will be considered as an improvement from baseline. | — |
Secondary
| Measure | Time frame |
|---|---|
| The pennation angle (PA), muscle thickness (MT) and fascicle length (FL) of the vastus lateralis muscle will be obtained using an ultrasound device (US) (Acuson X300 PE, Siemens) and linear transducer (4–11.4 MHz). The same previously trained evaluator, blinded to intervention groups, will obtain all images. The vastus lateralis was the chosen muscle for analysis due to the simple fascicle alignment when compared to the other quadriceps muscles. For image acquisition, the participants will be positioned supine with legs extended and relaxed muscles. Three vastus lateralis images will be collected at the midpoint of the thigh, measured as the midpoint between the greater trochanter and the lateral femoral epicondyle. Water-soluble gel will be applied between the transducer and the skin to aid in acoustical coupling and to prevent pressure muscle deformation. The transducer will be oriented parallel to the muscle fascicles during the image acquisition. A second investigator, also blinded to interventions group, will manually review all obtained images using the ImageJ software (National Institutes of Health, USA). PA will be defined as the insertion angle of the fascicle in the deep aponeurosis. MT will be defined as the distance between deep and superficial aponeurosis. FL will be defined as the distance between the origin of the fascicle in the superficial aponeurosis and the insertion of the same fascicle in the deep aponeurosis. The average of the three MT, PA and FL measurements will be used for analyses. The intra-rater reliability performed at one week interval was ICC = 0.97 (n=10).;The Pain Catastrophizing Scale (PCS) is a valid, reliable and self-applicable 13-item scale that describes thoughts and feelings that people may experience when they experience pain. Items are evaluated using a 5-point Likert scale, ranging from 0 to 4. The total score is calculated by the sum of the scores for all items (total score, 0-52). Higher scores indicate greater catast | — |
Countries
Brazil
Contacts
Public ContactJéssica Bianca Aily
Universidade Federal de São Carlos
Outcome results
None listed