FindTrial
Sign In

Effect of Coffee on the vascular reactivity of Overweight and Obese individuals

Acute effect of Coffee in the Endothelial Function of Overweight and Obesity individuals: A double-blind, randomized, cross-over clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-65cxtr
Enrollment
Unknown
Registered
2019-04-08
Start date
2019-01-28
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Interventions

Clinical trial, with double-blind and double-blind randomization, which will include two acute intervention periods (220 ml of caffeinated coffee and 220 ml of decaffeinated coffee), separated by anot
and the group that received decaffeinated coffee in the first intervention will receive caffeinated coffee in the second intervention. Twenty adult, overweight and obese individuals will be recruited
Other
D20.215.784.249
Z13.6

Sponsors

Universidade Federal de Santa Maria
Lead Sponsor
Universidade Federal de Santa Maria
Collaborator
CAPES - Coordenação de Aperfeiçoamento de Nível Superior
Collaborator

Eligibility

Age
25 Years to 59 Years

Inclusion criteria

Inclusion criteria: Individuals older than or equal to 25 years and less than 60 years; both sexes; low risk or intermediate cardiovascular risk characterized by the overall risk score; with overweight and obesity grade I according to the classification of the World Health Organization.

Exclusion criteria

Exclusion criteria: Individuals with high and very high cardiovascular risk, according to the Update of the Brazilian Dyslipidemias Directive and Prevention of Atherosclerosis; not have performed a lipid profile test in the last year; inability to ingest caffeine; infectious diseases active or treated in the last 30 days; neurological disease; type diabetes mellitus; familial dyslipidemia; smokers; hospitalization in the last 2 months; Renal insufficiency; hepatical cirrhosis; chronic obstructive pulmonary disease; coronary artery disease; cardiac insufficiency; atrial fibrillation; severe peripheral arterial insufficiency.

Design outcomes

Primary

MeasureTime frame
In a sample of overweight and obese adult individuals, it is expected that both the consumption of 220ml of caffeinated coffee and the same amount of decaffeinated coffee will promote the acute improvement of endothelial function.—

Secondary

MeasureTime frame
Secondary outcomes are not expected—

Countries

Brazil

Contacts

Public ContactPatrícia Chagas

Universidade Federal de Santa Maria

patriciachagas@ufsm.br+55-051-996690302

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 18, 2026