Inflammation
Conditions
Interventions
839/5000
Split mouth study, third molar extraction, intra-alveolar L-PRF compared with control side clot
In this study, 2 healthy patients with bilaterally included lower third molars were recruited.
Drug
Procedure/surgery
E06.892
A11.118
Sponsors
Universidade de Pernambuco
Universidade de Pernambuco
Faculdade de Odontologia da Universidade de Pernambuco
Eligibility
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: The established inclusion criteria are: age between 18 and 35 years old; no systemic disease; not to use medications that interfere with the procedure on the day or week prior to the research; present surgical site without current signs and symptoms of infection; agree to participate in the experiment; present lower third molars in similar positions.
Exclusion criteria
Exclusion criteria: Patients with: (1) history of pregnancy or lactation, (2) history of allergy to any drug used in the experiment; (3) not participate in all phases of the proposed research; (4) and not having the lower second molars.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to evaluate, with this study, to evaluate if L-PRF has a positive influence on the aveolar repair process after lower third molar extractions, increasing bone neoformation, which was evaluated by computed tomography. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is hoped with this study, to evaluate whether L-PRF is more effective in controlling pain and edema compared to negative control after lower third molar extraction. Verified by visual analog scale within 7 days (pain), 5 preoperative and 72h postoperative facial measurements (edema) | — |
Countries
Brazil
Contacts
Public ContactÉwerton Rocha Rodrigues
Universidade de Pernambuco
Outcome results
None listed