Apnea, general anesthesia, patient safety
Conditions
Interventions
This is a controlled clinical study where participants will be randomly divided into two groups. The participants will not know which group they are in. A total of 34 adult patients, 17 in high flow n
Sponsors
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients over 18 years of age of both genders; indicated for surgery requiring general anesthesia with endotracheal intubation; and invasive blood pressure, at Central Institute of Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Exclusion criteria
Exclusion criteria: Patient refusal; difficulty understanding and signing the informed consent form; moderate or severe pneumopathy (forced expiratory volume in 1 second less than 80% of predicted) or previous use of oxygen support, including prior intubation or tracheostomy; hemodynamic instability; predictors of difficult airway, for both ventilation and intubation; intracranial hypertension; patients at risk of bronchoaspiration, predictors of full stomach or ultrasonographic image of the gastric antrum confirming a large amount of content or solid content; Body Mass Index above 30 (obesity); confirmed pregnancy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a difference in arterial partial pressure of oxygen greater than 100 mmHg in the group oxygenated with high-flow nasal cannula after 5 min of apnea, compared to the regular nasal cannula | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in arterial partial pressure of carbon dioxide, serum potassium, and lactate will be evaluated, in addition to side effects such as headache and nasal bleeding | — |
Countries
Brazil
Contacts
Public ContactFernando Silva
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Outcome results
None listed