Skip to content

Clinical study to evaluate different adhesives in denture retention

Clinical, microbiological and patient-centered evaluation of different denture retention adhesives. Randomized crossover clinical study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-64gk7r
Enrollment
Unknown
Registered
2019-10-10
Start date
2019-08-26
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Halitosis

Interventions

Corega Adhesive ®-AC (control group): 25 individuals using upper and lower total dentures will be randomly allocated according to computer-generated numbers to begin denture adhesive use and remain fo
Other

Sponsors

Faculdade de Odontologia de Ribeirão Preto da Universidade de São Paulo.
Lead Sponsor
Faculdade de Odontologia de Ribeirão Preto da Universidade de São Paulo.
Collaborator

Eligibility

Age
18 Years to 90 Years

Inclusion criteria

Inclusion criteria: Being clinically satisfactory users of total maxillary and mandibular prostheses (duration of prosthesis use is 1 year or less); properly understand both spoken and written Portuguese; be able to provide informed consent; being able to understand the study procedures and have the ability to perform them

Exclusion criteria

Exclusion criteria: Presence of oral mucosal lesions such as denture-induced fibrous hyperplasia, papillomas or traumatic ulcerations associated with prosthesis bases or prosthesis-related stomatitis; Impaired cognitive function; Inability to attend returns for evaluation and maintenance; Patients on medications such as antibiotics, antifungals, immunosuppressants, anticoagulants and corticosteroids during the last 3 months prior to the survey.

Design outcomes

Primary

MeasureTime frame
Primary Variable - consider overall satisfaction and change patient-related symptoms using the McGill Satisfaction Questionnaire at baseline and end of study.

Secondary

MeasureTime frame
The evaluation of the ease of removal of the adhesives will be verified by weighing in a precision balance in three times, in the baseline and after 15 days of the use of the different adhesives. on the surface. The second weighing (M2) will be performed after the removal of the adhesive by ultrasound (5 min.). The mass 3 (M3) will correspond to the weight of the prosthesis after brushing to remove the adhesive.;Evaluation of the microbial load of the prostheses before and after the use of the adhesives will be performed by conventional culture methods from the phosphate buffered saline biofilm collected after ultrasound. The conventional method will provide the number of colony forming units (CFU) of the following microorganisms: candida spp., Gran-negatives and total aerobic.;Breath assessment before and after the use of adhesives. The oral breath and the odor of the prosthesis will be collected by digital halimeter at baseline consultations and 15 days after the use of the patches.

Countries

Brazil

Contacts

Public ContactCláudia Lovato da Silva

Faculdade de Odontologia de Ribeirão Preto da Universidade de São Paulo.

chl@forp.usp.br+55-16-32348934

Outcome results

None listed

Source: REBEC (via WHO ICTRP)