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Prevalence of risk factors for heart diseases in children and adolescents in Botuverá -SC: a continued study

Prevalence of cardiometabolic risk factors in children and adolescents of Botuverá-SC: a continued study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
REBEC
Registry ID
RBR-63wb6k
Enrollment
Unknown
Registered
2016-05-05
Start date
2015-03-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular disease, obesity, diabetes, hipertension, dyslipidemia.

Interventions

Observational study. All students enrolled in public schools in the city of Botuverá-SC (n = 587) were invited to participate. Sample calculation determined that 356 children would be the minimum numb
Other

Sponsors

Universidade Federal de Santa Catarina
Lead Sponsor
Edson Luiz da Silva
Collaborator

Eligibility

Age
6 Years to 16 Years

Inclusion criteria

Inclusion criteria: Be enrolled in a public school of the city of Botuverá-SC, both genders.

Exclusion criteria

Exclusion criteria: Not included exclusion criteria.

Design outcomes

Primary

MeasureTime frame
Expected to observe the occurrence of dyslipidemias in the students, evaluated by the concentration of total cholesterol, low density lipoprotein cholesterol (LDL-C), cholesterol in the small and dense fraction of low density lipoprotein (sd-LDL), triglycerides, cholesterol of high density lipoproteins (HDL-c). The values will be presentead as percentage. Differences between the genders are evaluated by Student t-test or Mann Whitney test for parametric and non-parametric data, respectively, and p less or equal 0.05 will be considered significant.;49.6% of students had high values of total cholesterol and 25.8 % borderline values. high and borderline values of low density liproprotein (LDL-c) were found in 16.3% and 33.8 % of students, respectively, and 18.0 % of students had more atherogenic low density lipoprotein (LDL) pattern, based on the value of small and dense fraction of low density lipoprotein (sd- LDL-c) levels greater than 50 % of low density lipoprotein (LDL-c). Low high density lipoprotein (HDL-c) was observed in 20.8 % of children and adolescents. High and borderline triglyceride concentrations were found in 6.0% and 12.5 % of subjects, respectively.

Secondary

MeasureTime frame
Expected to observe the prevalence of prehypertension and hypertension, through the measurement of systolic and diastolic blood pressure and stratification by gender, age and height according to the world health organization (WHO). The values will be presentead as percentage. Differences between the genders are evaluated by Student t-test or Mann Whitney test for parametric and non-parametric data, respectively, and p less or equal 0.05 will be considered significant.;High levels of blood pressure were observed in 31.1 % of children and adolescents, and prehypertension was observed in 14.0 % of participants, hypertension level I and II in 11.8 % and 5.3 % of students respectively. There were no differences in prevalence between boys and girls.;Expected to observe the occurrence of subclinical inflammation, through the analysis of C-reactive protein of high sensitivity (hs-CRP) and uric acid. The values will be displayed as percentage. Differences between the genders are evaluated by Student t-test or Mann Whitney test for parametric and non-parametric data, respectively, and p less or equal 0.05 will be considered significant.;The prevalence of children and adolescents with C-reactive protein of high sensitivity (hs-CRP) concentration within the border and high values was 15.4 % and 8.3 %, respectively. Hyperuricemia was present in 5.8% of children and adolescents.;Expected to observe the occurrence of diabetes and insulin resistance through the glucose and insulin analysis and calculating the homeostatic model assesment (Homai). The values will be displayed as percentage. Differences between the genders are evaluated by Student t-test or Mann Whitney test for parametric and non-parametric data, respectively, and p less or equal 0.05 will be considered significant.;14% of subjects had fasting glucose concentration above recommended. Insulin values were in the borderline range in 5.4% of children and adolescents and increased in 1.3 %. The prevalence of hyperinsulin

Countries

Brazil

Contacts

Public ContactHeloisa Cunha

Universidade Federal de Santa Catarina

helopc@hotmail.com+55(48)99976966

Outcome results

None listed

Source: REBEC (via WHO ICTRP)