Neoplasias Colorretais Hereditárias sem Polipose
Conditions
Interventions
Experimental group: 30 patients at high risk with polyps identified in the screening colonoscopy will receive green tea supplementation (standard dry extract) through 2 750mg capsules after the 2 main
Dietary supplement
Sponsors
A.C.Camargo Cancer Center
Essentia Farmácia Homeopática
Eligibility
Age
20 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients older than 20 years with Lynch syndrome with a mutation identified or meeting Amsterdam criteria will be included in the study with colonic colonoscopy of the screening colonoscopy; participants who agree to participate in the research by signing the Free and Informed Consent Form.
Exclusion criteria
Exclusion criteria: Presence of inflammatory bowel disease (such as ulcerative colitis and Crohn's disease); history of organ transplantation or co-administration of immunosuppressive drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a reduction in the onset of metachronic polyps within one year, verified by colonoscopy or rectosigmoidoscopy, with a 50% decrease after intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to characterize as reliably as possible the relationship between the intake of green tea extract and the appearance of metachronic polyps with nutritional status, using body mass index and waist circumference in pre and post-intervention measurements. ;It is expected to characterize as reliably as possible the relationship between the eating habits of the patients in question and the appearance of metachronic polyps, using a validated food frequency questionnaire in pre and post-intervention measurements. | — |
Countries
Brazil
Contacts
Public ContactMelissa;Ranyell Rotatori;Batista
A.C.Camargo Cancer Center;A.C.Camargo Cancer Center
Outcome results
None listed