Chronic Cough
Conditions
Interventions
This is a randomized controlled double-blind clinical trial with two parallel arms. Thirty-one participants diagnosed with refractory chronic cough were randomized through the Random dot org platform
Sponsors
Escola Paulista de Medicina da Universidade Federal de São Paulo
Universidade Federal de São Paulo
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: People over 18 years old; regardless of gender; diagnosed with Refractory chronic cough
Exclusion criteria
Exclusion criteria: Illiterate individuals; individuals without autonomy to provide assent to participate in the research
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| No secondary outcomes are anticipated | — |
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: A reduction of at least 17.5 points in the total score of the Cough Severity Index – Brazilian version is expected, indicating a decrease in the severity of refractory chronic cough. This will be verified through comparisons of measurements taken before the intervention, immediately after, one month, and three months after the end of the speech-language therapy intervention. Observed outcome 1: A significant reduction in the total score of the Cough Severity Index – Brazilian version was observed, with better results three months after the end of the speech-language therapy intervention (p < 0.05). Group 1 presented significantly lower scores than Group 2 (p < 0.001), indicating a greater reduction in the severity of refractory chronic cough.;Outcome found 1: A 35% reduction in the frequency of cough episodes was identified over a 12-week period, measured by an electronic symptom diary, when comparing baseline values with those obtained after the intervention. | — |
Countries
Brazil
Contacts
Public ContactRodrigo Dornelas
Universidade Federal de São Paulo
Outcome results
None listed