Cognitive dysfunction
Conditions
Interventions
Sponsors
Universidade de Pernambuco - UPE (Campus Petrolina)
Universidade de Pernambuco - UPE (Campus Petrolina)
Eligibility
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: We will recruit older adults, 65 years and older, with MOTORIC Cognitive Risk Syndrome
Exclusion criteria
Exclusion criteria: We will exclude participants who have the following criteria. not being able to speak and understand the Portuguese; not being able to walk at least 10 meters without mobility aids (eg, cane); participate in structured physical exercise programs for at least 3 months; have exacerbated walking impairment due to musculoskeletal disorders or neurological motor deficit (eg, severe osteoarthritis, lower limb amputation, Parkinson's disease, stroke with motor sequelae); use antipsychotic-type drugs, have a diagnosis of major depression or any-type dementia; have unstable cardiovascular or metabolic diseases (eg, angina pectoris, decompensated diabetes) or chronic complications (eg, retinopathy, neuropathy) that precludes structure exercise engagement; not having adequate visual and auditory capacity to perform the cognitive assessments
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To assess the changes in physical function through the Short Physical Performance Battery scores (0-12) from baseline to 24-weeks follow-up;To assess the changes in global cognitive function through the Montreal Cognitive Assessment (0-30) scores from baseline to 24-weeks follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| To assess the changes in executive functioning through measures of Trail Making Test A (in seconds), Digit Span of WAIS-III (score) and verbal fluency (animal naming) from baseline to 24-weeks follow-up;To assess the changes in mobility and dynamic balance through measures of gait-related variables and scales such 6-meters walking speed test (in m/s), Timed Up and Go (in seconds) and Activities-specific Balance Confidence scale (scores) from baseline to 24-weeks follow-up;To assess the changes in muscle strength and upper limb power through measures of leg extension peak of torque (in Nm) and seated Medicine Ball throw (distance in meters) from baseline to 24-weeks follow-up;To assess the changes in muscular thickness of quadriceps (body composition) through Ultrasonography (in m3) from baseline to 24-weeks follow-up;To assess the changes in blood pressure (in mmHg), heart-rate variability parameters and vascular health parameters (using different units) through a blood pressure monitor, cardiac monitor and ultrasonography, respectively, from baseline to 24-weeks follow-up;To assess the changes in time spent in physical activities and sedentary behaviour (as measures of healthy behaviours) in minutes/week using smartwatch based-technologies or accelerometers from baseline to 24-weeks follow-up;To assess the changes in health-related quality of life through questionnaire (in scores) from baseline to 24-weeks follow-up | — |
Countries
Brazil
Contacts
Public ContactRodrigo de Araújo
Universidade de Pernambuco - UPE (Campus Petrolina)
Outcome results
None listed