Inflammation
Conditions
Interventions
Control group will be the group with 15 individuals who will not receive the intervention of the fat solution with extra virgin olive oil
Experimental group with 0.25 will be the group with 15 individ
D26.255.165.260.270
Sponsors
Universidade Regional do Noroeste do Estado do Rio Grande do Sul - UNIJUI
Universidade de Jaén
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: All patients over 18 years of age; more than six months in hemodialysis treatment; with adequate dialysis index greater than 1.2
Exclusion criteria
Exclusion criteria: Not accepting to be part of the research; chemotherapy or radiotherapy in the last three months; corticosteroid therapy greater than 7.5 mg/d; acute bacterial infection; impairment of vascular access; severe liver failure; acute immunodeficiency virus; severe hypertriglyceridemia above 400 mg; difficulty in adjusting blood glucose; pregnancy; hypersensitivity to any component of the lipid emulsion; intrahepatic cholestasis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Decrease in the inflammatory state within a period of four weeks, verified by infusing the lipid emulsion with extra virgin olive oil at a dose of 0.25 mg/d of body weight, applied during hemodialysis, from the observation of at least 5 % in pre- and post-intervention inflammatory cytokine measurements | — |
Secondary
| Measure | Time frame |
|---|---|
| Improvement in nutritional status in a period of four weeks, verified by infusion of lipid emulsion with extra virgin olive oil at a dosage of 0.25 mg/d of body weight applied during hemodialysis, from the observation of at least 5% pre- and post-intervention serum albuminia measurements | — |
Countries
Brazil
Contacts
Public ContactOlvânia Oliveira
Universidade de Jaén
Outcome results
None listed