Periapical Abscess Stomatognathic Diseases
Conditions
Interventions
This is an observational, controlled, non-randomized clinical study, with a total of 26 participants of both sexes, aged 18 years or older, who meet the inclusion criteria and will be classified accor
Sponsors
Faculdade de Odontologia de Araçatuba - Universidade Estadual Paulista
Faculdade de Odontologia de Araçatuba - Universidade Estadual Paulista
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Participants of both sexes; minimum age of 18 years; systemically healthy individuals; absence of periodontitis. Patients with chronic apical abscess; absence of pain; presence of periapical lesion; presence of sinus tract; teeth without direct pulp exposure to the oral cavity; teeth suitable for rubber dam isolation; teeth from any dental group. For the control group asymptomatic individuals; absence of carious lesions; absence of inflammatory lesions; absence of neoplastic lesions
Exclusion criteria
Exclusion criteria: Presence of systemic diseases; continuous use of medications; history of chemotherapy or radiotherapy; use of antibiotics within the three months prior to sample collection; current or past smoking; ongoing orthodontic treatment; presence of periodontal disease. For the chronic apical abscess group presence of teeth with vital pulp; absence of periapical lesion; absence of sinus tract; severely destroyed crown preventing proper isolation; pulp tissue exposed to the oral cavity; history of previous endodontic treatment in the tooth of interest. For the control group presence of carious lesions; presence of inflammatory lesions; presence of neoplastic lesions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| In saliva, variation in the levels of thiobarbituric acid reactive substances, nitrite, total antioxidant capacity, and uric acid, measured at baseline (active disease) and at follow-up (1 month) after endodontic treatment, comparing individuals in the control group and patients with chronic apical abscess at baseline, as well as patients with chronic apical abscess at baseline and at follow-up | — |
Secondary
| Measure | Time frame |
|---|---|
| In saliva, variation in unstimulated salivary flow rate, buffering capacity, pH, calcium, phosphate, chloride, total protein, alkaline phosphatase, total acid phosphatase, tartrate-resistant acid phosphatase, and transaminases, measured at baseline (active disease) and at follow-up (1 month) after endodontic treatment, comparing individuals in the control group and patients with chronic apical abscess at baseline, as well as patients with chronic apical abscess at baseline and at follow-up | — |
Countries
BR
Contacts
Public ContactRogério Jacinto
Faculdade de Odontologia de Araçatuba - Unesp
Outcome results
None listed