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Effect of zinc supplementation in patients with ulcerative colitis

Effect of zinc supplementation on inflammatory markers in ulcerative colitis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5yrjrr4
Enrollment
Unknown
Registered
2021-09-17
Start date
2018-06-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ulcerative Colits

Interventions

40 patients were supplemented, for thirty days, with zinc gluconate containing the daily recommendation (Institute of Medicine-IOM, 2006) of the mineral adjusted for sex. Male patients received 79 mg/
D01.975
G07.203.300.456

Sponsors

REGINA MÁRCIA SOARES CAVALCANTE
Lead Sponsor
UNIVERSIDADE FEDERAL DO PIAUÍ
Collaborator

Eligibility

Age
18 Years to 69 Years

Inclusion criteria

Inclusion criteria: Patients diagnosed with ulcerative colitis (with at least 6 months of diagnosis time);non-smokers; without coexisting pathologies such as diabetes; hypertension and kidney disease;cardiovascular diseases; rheumatic diseases and any other diseases involving an inflammatory process; without the use of a vitamin-mineral supplement; who voluntarily agreed to participate in the research, with the consent materialized by signing the Informed Consent Term.

Exclusion criteria

Exclusion criteria: Patients who changed city and/or state; who did not have telephone contact;who discontinued use of the supplement; who did not attend the collection of biological material

Design outcomes

Primary

MeasureTime frame
Supplementation with zinc gluconate recovered the nutritional status of patients in relation to the mineral, however there was no correlation between plasma and erythrocyte zinc levels and the cytokines analyzed (IL-2, IL-4, IL-6, IL-10 , IFN-? and TNF-a) at any time of supplementation.

Countries

Brazil

Contacts

Public ContactRegina Cavalcante
reginalunna@hotmail.com+5586994333733

Outcome results

None listed

Source: REBEC (via WHO ICTRP)