Portal hypertension
Conditions
Interventions
Experimental group (Portal hypertension - group I): we included 28 patients diagnosed with portal hypertension, these patients were characterized by the presence of esophageal varices, with or without
Procedure/surgery
Sponsors
Faculdade de Ciências Médicas da Santa Casa de São Paulo - FCMSCSP
Fundação Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Eligibility
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: The study included 69 volunteers of both sexes; from 18 to 80 years of age; presenting elevated antral erosions during endoscopy; with or without portal hypertension.
Exclusion criteria
Exclusion criteria: The volunteers who had prior treatment to eradicate Helicobacter pylori; who had recently used antibiotics or who have not agreed to participate in the study were excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The elevated antral erosions in patients with portal hypertension, although identical in appearance by endoscopy to those elevated erosions in patients without portal hypertension, histologically are different entities. ;After finishing the study we found that elevated antral erosions in patients with portal hypertension are the result of edema and vascular congestion, different from patients without portal hypertension which are the result of inflammatory infiltrate, when analyzed the biopsies performed by endoscopy, with 95% for sure. | — |
Secondary
| Measure | Time frame |
|---|---|
| The presence of H pylori may be an aggravating factor that justifies the presence of inflammation in the whole sample.;After conducting the study we did not find a statistically significant difference from the presence of H. pylori and inflammatory infiltrate. | — |
Countries
Brazil
Contacts
Public ContactFabio;Fabio Ferreira;Ferreira
Faculdade de Ciências Médicas da Santa Casa de São Paulo - FCMSCSP;Faculdade de Ciências Médicas da Santa Casa de São Paulo - FCMSCSP
Outcome results
None listed