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Effects of Progressive Muscle Strengthening and Whole Body Vibration in Older Adults with Type II Diabetes

Effects of whole-body vibration combined with progressive resistance exercise on muscle strength, functional capacity, body composition, and biological parameters in older adults with type II diabetes: a single-blind randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5xs4bp9
Enrollment
Unknown
Registered
2025-10-16
Start date
2024-07-30
Completion date
Unknown
Last updated
2025-11-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle strength

Interventions

This is a randomized, parallel-group clinical trial with a superiority structure and single-blind (evaluators). Experimental group: 29 older adults who will perform progressive resistance exercises (P
40 min) for a period of 12 weeks. The training will consist of dynamic exercises of squatting, hip abduction and flexion and plantar flexion. The WBV will begin with 30 seconds of vibration at 30 Hert
other exercises will start at 50% of 1 repetition maximum (1RM) and will progress to 75 to 80% of 1RM. Muscle strength, functional capacity, muscle quality, laboratory tests, body composition and bone

Sponsors

Universidade Federal de Minas Gerais
Lead Sponsor
Universidade Federal de Viçosa
Collaborator

Eligibility

Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: Be 60 years of age or older; have a medical diagnosis of Type II Diabetes; be considered active based on the results of the International Physical Activity Questionnaire; be independent in walking; have signed the free and informed consent form

Exclusion criteria

Exclusion criteria: Type 1 Diabetes; renal and hepatic insufficiency; retinopathy; plantar injuries; previous history of cerebral aneurysm; neurological diseases (Parkinson's, stroke, traumatic brain injury, spinal cord injuries and multiple sclerosis); cognitive alterations detected in the Mini Mental State Examination (MMSE) (score = 13 for illiterates, = 18 for low and medium and = 26 for high education); current oncological treatment; Present signs of thrombosis; pacemaker wearer; presence of metal implants; have orthopedic limitations that prevent training on the platform or tests; recent surgeries or fractures (= 4 months); having received whole body vibration treatment in the last six months

Design outcomes

Primary

MeasureTime frame
It is expected to find an improvement in the voluntary strength of the Maximum Voluntary Isometric Contraction (MVIC) of the knee extensors measured by the load cell, as well as in the maximum dynamic strength of the knee extensors, assessed one week before and up to one week after the interventions. The results will be compared between groups, and the group that received vibration associated with resistance exercises is expected to show at least a 5% greater improvement compared to the control group that did not receive vibration;It is expected to find an improvement in usual and fast walking speeds over a 4-meter distance, assessed one week before and up to one week after the interventions. The results will be compared between groups, and the group that received vibration associated with resistance exercises is expected to show at least a 5% greater improvement compared to the control group that did not receive vibration;It is expected to find an improvement in functional capacity measured by the Timed Up and Go (TUG) test, assessed one week before and up to one week after the interventions. The results will be compared between groups, and the group that received vibration associated with resistance exercises is expected to show at least a 5% greater improvement compared to the control group that did not receive vibration

Secondary

MeasureTime frame
It is expected to find an improvement in laboratory tests measured one week before and up to one week after the interventions, including fasting glucose, glycated hemoglobin, pro-inflammatory markers – TNF, soluble TNF receptor 1 (sTNF-R1), and C-reactive protein (CRP) – and neurotrophin: Brain-Derived Neurotrophic Factor (BDNF). The results will be compared between groups, and the group that received vibration associated with resistance exercises is expected to show at least a 5% greater improvement in the measured parameters compared to the control group that did not receive vibration;It is expected to find an improvement in functional capacity measured by the Bipodal Static Balance Test, assessed one week before and up to one week after the interventions, in three positions held for 10 seconds each with eyes open: standing with feet together, standing with one foot partially in front, and standing with one foot fully in front. The results will be compared between groups, and the group that received vibration associated with resistance exercises is expected to show at least a 5% greater improvement compared to the control group that did not receive vibration;It is expected to find an improvement in functional capacity measured by the Five Times Sit-to-Stand Test (FTSST), assessed one week before and up to one week after the interventions. The results will be compared between groups, and the group that received vibration associated with resistance exercises is expected to show at least a 5% greater improvement compared to the control group that did not receive vibration;It is expected to find an improvement in bilateral handgrip strength, measured with a hand dynamometer one week before and up to one week after the interventions. The results will be compared between groups, and the group that received vibration associated with resistance exercises is expected to show at least a 5% greater improvement compared to the control group that did not receive vibration;It i

Countries

Brazil

Contacts

Public ContactDaniele Pereira

Escola de Educação Física, Fisioterapia e Terapia Ocupacional da Universidade Federal de Minas Gerais

danielesirineu@gmail.com+55(31)34097395

Outcome results

None listed

Source: REBEC (via WHO ICTRP)