Skin Aging
Conditions
Interventions
In the study, sixty participants will be selected. sign the informed consent The participants will be randomly distributed into two groups through a lottery keeping confidentiality with sealed opaque
A15.145.693.600
G13.750
Sponsors
Universidade Brasil
Universidade Brasil
Eligibility
Sex/Gender
Female
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: women; age range of 40 and 60 years; phototype II to IV according to the Fitzpatrick scale; presence of signs of facial photoaging grade II to IV according to the Glogau scale; blood count with normal platelet count (150,000 to 350,000 uL); consent to participate in the study to sign the informed consent;
Exclusion criteria
Exclusion criteria: smokers; pregnant or breastfeeding women; history of neoplasia; ablative chemical or physical peeling in the last 6 months; use of botulinum toxin or fillers with facial implants with absorbable material in the last six months; performance of surgical procedures (rhytidoplasty and/or blepharoplasty); patient unable to use photoprotection throughout the treatment period; patients with a history of keloids or hypertrophic scarring; patients with infected or inflamed skin lesion on the face in the last 12 months; underlying diseases such as uncontrolled systemic arterial hypertension; renal liver disease; hematological (coagulopathies and/or purpura, glucose 6-phosphate deficiency); inflammatory; rheumatological; with diabetes; platelet count below 150,000/uL; of hypersensitivity to ozone therapy treatment; refusal to sign the informed consent form; still, the discontinuity criteria were established: withdrawal of the participants; two consecutive absences; present any disorder/infection that implies the use of antibiotics throughout the study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate and compare the effects of Platelet Rich Plasma (PRP) and its association with ozone therapy on skin aging using the Global Aesthetic Improvement Scale | — |
Secondary
| Measure | Time frame |
|---|---|
| Evaluate self-esteem using the Brazilian version of the Rosenberg Self-Esteem Scale ;Evaluate treatment satisfaction through the Perception of Global Effect | — |
Countries
Brazil
Contacts
Public ContactCarla de Camargo
Universidade Brasil
Outcome results
None listed