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The impact of Strength Training and Vitamin D on muscle loss and Obesity throughout aging

Effects of Muscle Strength Training Combined with Vitamin D Supplementation in Elderly Individuals with Sarcopenic Obesity

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5x7p5zy
Enrollment
Unknown
Registered
2025-10-08
Start date
2022-01-05
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aging

Interventions

Randomization was carried out according to the age and sex of the participants. The study was blinded for both participants and the researcher regarding the Vitamin D intervention, although it could n

Sponsors

Universidade do Estado do Rio de Janeiro- Instituto de Educação Física e Desporto
Lead Sponsor
Universidade do Estado do Rio de Janeiro- Instituto de Educação Física e Desporto
Collaborator

Eligibility

Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: Elderly people, who are able to practice muscle strength training. Minimum age 60 years old. Both genders. Who have normal absorption of vitamin D, according to the age group studied. All persons must have signed the Informed Consent Form

Exclusion criteria

Exclusion criteria: People under 60 years of age. People, who despite being elderly, are not able to practice strength training due to cognitive or osteoarticular limitations. People with diseases that reduce or inhibit the absorption of vitamin D and bariatric surgery

Design outcomes

Primary

MeasureTime frame
Evaluate muscle strength. It is expected to find an improvement in the strength of upper and lower limbs in all groups, however it is expected that the group that underwent combined training with Vitamin D supplementation will have the best result. The strength of the upper limbs will be assessed by manual dynamometry and the strength of the lower limbs will be assessed by the sit-to-stand test.;Assess body composition: body fat percentage, total fat, total muscle mass, appendicular muscle mass. It is expected that both groups will experience a decrease in body fat percentage and total fat, as well as an increase in total muscle mass and appendicular lean mass. However, better results are expected in the group that combined training and Vitamin D. The method used to obtain these results is the Dexa Scan.;Evaluate inflammatory status: tumor necrosis factor alpha a (TNF-a) and interleukin 6 (IL-6). It is expected that both groups will have decreased expression of inflammation markers. However, it is anticipated that the group that combined training and Vitamin D will have a better outcome. The method for evaluation is through blood sample assessment, using the Cytokine/Chemokine Magnetic bead panel Kit (EMD Millipore Corporation) for evaluation.

Secondary

MeasureTime frame
Evaluation of muscle strength. It is expected to find improvement in muscle strength of upper and lower limbs in both groups, however, the group that received the training intervention and Vitamin D will have a better outcome. The method for evaluation was the comparison of muscle strength in each exercise, at the beginning and at the end of the 12-week intervention, the exercises are: leg press, bench press, leg extension machine, seated row, leg curl machine, pulley pull down, calf raise on leg.

Countries

Brazil

Contacts

Public ContactNádia Da Silva

Universidade do Estado do Rio de Janeiro

nadiaslimas@gmail.com+55 (21) 968077667

Outcome results

None listed

Source: REBEC (via WHO ICTRP)