Mild Cognitive Disorder
Conditions
Interventions
The study will utilize a randomized experimental design. This is an open-label (unmasked) study. Participants will be randomly divided into two groups: The control group will consist of 12 individuals
F01.145.666
Sponsors
Universidade Estadual do Sudoeste da Bahia
Universidade Estadual do Sudoeste da Bahia
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: this study will include adults over the age of 18 who are part of the jequié ativo program or who want to participate of their own free will in a physical exercise program in the community
Exclusion criteria
Exclusion criteria: pregnant women; those with severe heart disease and those with persistent hypertension will be excluded from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The expected improvement in participants' global cognitive status will be verified using the Mini-Mental State Examination (MMSE), with the outcome determined by an increase in the total score post-intervention compared to baseline | — |
Secondary
| Measure | Time frame |
|---|---|
| An improvement in executive function (cognitive flexibility and processing speed) is expected in the dual-task group over the control group, assessed by the Stroop Color and Word Test. This will be confirmed by a reduction in response time and number of errors on the incongruent condition when comparing the baseline data to subsequent quarterly assessments;An improvement in intracranial compliance (ICC) is expected, assessed via the Brain4care® non-invasive monitoring device, with the outcome observed as an improvement in the intracranial pressure (ICP) pulse wave morphology (p2/p1 ration) when comparing baseline data with subsequent assessments.;An improvement in cardiac autonomic modulation is expected, verified by the analysis of heart rate variability (HRV) using the Polar H10 heart rate monitor. The outcome will be confirmed by an improvement in HRV indices in the time and frequency domains, comparing baseline data with measurements taken throughout the study;An expected reduction in resting blood pressure will be measured using a validated automatic digital blood pressure monitor (OMRON). The outcome will be determined by a decrease in systolic (SBP) and diastolic (DBP) blood pressure values in post-intervention measurements compared to the pre-intervention baseline;An expected improvement in recognition memory performance and cognitive reaction time will be assessed with the MemTrax online cognitive performance test. The outcome will be determined by an increase in the percentage of correct responses (MTXcorrect) and reaction speed (MTXspeed) across the 5 measurements of the study;An expected improvement in perceived quality of life will be verified using the Short-Form 36-Item Health Survey (SF-36). The outcome will be determined by an increase in the scores across the eight domains, as well as in the physical (PCS) and mental (MCS) component summaries, in post-intervention results compared to the pre-intervention baseline | — |
Countries
Brazil
Contacts
Public ContactAlinne Oliveira
Universidade Estadual do Sudoeste da Bahia
Outcome results
None listed