Third molar
Conditions
Interventions
This randomized, double-blind, controlled clinical study aims to evaluate the effect of a green tea and hyaluronic acid-based mouthwash on alveolar repair in post-extraction sites of third molars comp
Chlorhexidine (CLO) (n=20): Patients will use a mouthwash with 0.12% chlorhexidine
Green tea/Hyaluronic acid (CV/HA) (n=20): Patients will use a mouthwash with green tea and hyaluronic acid. Patients will be randomly allocated to the groups. Patients will be instructed to rinse thei
Sponsors
Associação Salgado de Oliveira de Educação e Cultura
Centro Universitário do Triângulo - UNITRI
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Patients must be over 18 years of age; Patients must have good oral hygiene (plaque index < 20%); Patients must have all four third molars and be indicated for extraction of all third molars
Exclusion criteria
Exclusion criteria: Patients with periodontal disease; Patients with systemic diseases or conditions or who use medications that alter bone metabolism (except diabetics); Uncontrolled diabetics (glycated hemoglobin above 8%); Pregnant or breastfeeding women; Heavy smokers (more than 10 cigarettes daily); Presence of periapical lesions
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary variable in this study will be pain assessment using the visual analog scale, and it is expected that the Chlorhexidine and Green Tea/Hyaluronic Acid groups will present pain levels that will not differ from each other by more than 2 points on the visual analog scale | — |
Secondary
| Measure | Time frame |
|---|---|
| The assessment of wound healing will be performed using a wound healing index. It is expected that the Chlorhexidine and Green Tea/Hyaluronic Acid groups will exhibit wound healing levels that will not differ from each other by more than 2 points on the tissue wound healing index;Edema analysis will be performed through mouth opening assessments and facial measurements. It is expected that the Chlorhexidine and Green Tea/Hyaluronic Acid groups will present facial and mouth opening measurements that will not differ from each other by more than 5 mm for mouth opening and 2 mm for facial measurements;Bone healing analysis will be performed using radiographic bone density and fractal dimension analysis. It is expected that the Chlorhexidine and Green Tea/Hyaluronic Acid groups will present radiographic density and fractal dimension levels that will not differ from each other by more than 10% | — |
Countries
Brazil
Contacts
Public ContactRoberto Pessoa
Centro Universitário do Triângulo - UNITRI
Outcome results
None listed