Dental caries
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Children between 3 and 12 years of age with primary or permanent molars having active deep caries lesion and without pulp involvement
Exclusion criteria
Exclusion criteria: Children whose guardians refused to sign the informed consent document; children who do not cooperate with the clinical examination; with syndromes or chronic systemic diseases; teeth with painful symptoms consistent with irreversible pulpitis or mobility; periodontal changes; roots with pathological resorption; cases of primary teeth roots in advanced stage of physiological resorption and patients who have made use of any antibiotics during the study period or within three months before its initiation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The expected outcome is to obtain clinical success, achieving the reduction of microorganisms. We will collect dentin sample before and after the treatment (TFDa). Seven days after sample processing, we will done the colony forming units (CFU) count in these two moments. After applying appropriate statistical tests we will compare the frequency reduction of microorganisms related to the onset and progression of caries as microorganisms total, total Streptococcus, Streptococcus mutans and Lactobacillus. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary expected outcome is the reduction of microorganisms unrelated to the initiation and development of dental caries but in several studies are also found in carious lesions such as Candida and the Enterococcus faecalis. We also will collect dentin sample before and after the treatment (TFDa). Seven days after sample processing, we will done the colony forming units (CFU) count in these two moments. After applying appropriate statistical tests we will compare the frequency reduction of these microorganisms. | — |
Countries
Brazil
Contacts
Faculdade de Odontologia - Universidade Federal Fluminense