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Evaluation of the use of laser for treatment in children's deep caries.

Use of antimicrobial Photodynamic Therapy as an adjunct in reducing microorganisms of the oral cavity

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5wddpz
Enrollment
Unknown
Registered
2016-12-29
Start date
2016-03-21
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dental caries

Interventions

The same teeth wil be the case and control once the aim of this resarch is to detect the microorganisms reduction after appling a laser wir lower power (antimicrobial photodinamic therapy _aPDT). So
Radiation
E02.186.500

Sponsors

Faculdade de Odontologia - Universidade Federal Fluminense
Lead Sponsor
Faculdade de Odontologia - Universidade Federal Fluminense
Collaborator

Eligibility

Age
3 Years to 12 Years

Inclusion criteria

Inclusion criteria: Children between 3 and 12 years of age with primary or permanent molars having active deep caries lesion and without pulp involvement

Exclusion criteria

Exclusion criteria: Children whose guardians refused to sign the informed consent document; children who do not cooperate with the clinical examination; with syndromes or chronic systemic diseases; teeth with painful symptoms consistent with irreversible pulpitis or mobility; periodontal changes; roots with pathological resorption; cases of primary teeth roots in advanced stage of physiological resorption and patients who have made use of any antibiotics during the study period or within three months before its initiation.

Design outcomes

Primary

MeasureTime frame
The expected outcome is to obtain clinical success, achieving the reduction of microorganisms. We will collect dentin sample before and after the treatment (TFDa). Seven days after sample processing, we will done the colony forming units (CFU) count in these two moments. After applying appropriate statistical tests we will compare the frequency reduction of microorganisms related to the onset and progression of caries as microorganisms total, total Streptococcus, Streptococcus mutans and Lactobacillus.

Secondary

MeasureTime frame
The secondary expected outcome is the reduction of microorganisms unrelated to the initiation and development of dental caries but in several studies are also found in carious lesions such as Candida and the Enterococcus faecalis. We also will collect dentin sample before and after the treatment (TFDa). Seven days after sample processing, we will done the colony forming units (CFU) count in these two moments. After applying appropriate statistical tests we will compare the frequency reduction of these microorganisms.

Countries

Brazil

Contacts

Public ContactLivia Antunes

Faculdade de Odontologia - Universidade Federal Fluminense

liviaazeredo@yahoo.com552225287166

Outcome results

None listed

Source: REBEC (via WHO ICTRP)