non-cavitated enamel carious lesions (white spot lesions) in permanent teeth in children
Conditions
Interventions
Experimental Group 1: 20 participants (aged 7-11 years) will be treated with fluoride varnish of 4% titanium tetrafluoride (2.45% F, pH 1, FGM-DentsCare) on all smooth faces of the permanent teeth for
Drug
Other
Sponsors
Universidade de São Paulo
Faculdade de Odontologia de Bauru - FOB/USP
Universidade de São Paulo
Eligibility
Age
7 Years to 12 Years
Inclusion criteria
Inclusion criteria: Signature of parents or guardians, the Informed consent. Present active white spot lesions (scale 1 Nyvad et al., 2003) on smooth surfaces of at least two teeth in the initial clinical examination.
Exclusion criteria
Exclusion criteria: users of orthodontic appliances; That participated in another clinical trial within 3 months prior to the selection or subjected to professional fluoride application in the last 6 months; treatment with antibiotics or some other type of medicine (with chronic diseases);with periodontal disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1) prevention of cavitated carious lesions evaluated by the DMFT index after 18 months of intervention; 2) reversal or progression of enamel lesions previously active non-cavitated present on smooth surfaces evaluated using the Nyvad index after 18 months of intervention; 3) reversal or progression of enamel lesions previously active non-cavitated present on smooth surfaces assessed by the change in fluorescence and area of lesions using QLF after 18 months of intervention. | — |
Secondary
| Measure | Time frame |
|---|---|
| 2) reversal or progression of enamel lesions previously active non-cavitated present on smooth surfaces evaluated using the Nyvad index after 1, 6 and 12 months of intervention; 3) reversal or progression of enamel lesions previously active non-cavitated present on smooth surfaces assessed by the change in fluorescence and area of lesions using QLF after 1, 6 and 12 months of intervention. | — |
Countries
Brazil
Contacts
Public ContactBeatriz Martines de Souza
Faculdade de Odontologia de Bauru - FOB/USP
Outcome results
None listed