Hypertension
Conditions
Interventions
The study will be carried out with a cross over design, that is, all participants will perform the five procedures, with the order of procedures determined at random by a researcher not involved in th
G07.203.300.456
Sponsors
Ufpb - Universidade Federal da Paraiba
Ufpb - Universidade Federal da Paraiba
Eligibility
Age
40 Years to 60 Years
Inclusion criteria
Inclusion criteria: Volunteers diagnosed with hypertension according to the seventh Brazilian Guidelines on Hypertension; with SBP between 130 and 160 mmHg and DBP between 85 and 90 mmHg; using antihypertensive drugs; except for the beta-blocker class; are not assiduous consumers of beetroot; have a recent history in the last month of performing aerobic exercises with sessions of at least 60 minutes; not being a smoker and being able to carry out the protocol of physical exercise
Exclusion criteria
Exclusion criteria: Volunteers who do not participate in all experimental procedures; present gastrointestinal discomfort to beetroot juice or control drink; change the medication, diet or physical training pattern during the experimental procedures
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find a reduction in pressure levels and an increase in the duration of post-exercise hypotension after an exercise session in procedures with beetroot juice ingestion in hypertensive individuals; verified by ambulatory blood pressure monitoring, with the magnitude presented in mmHg and the duration in hours | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected that there will be an increase in serum concentrations of total antioxidant capacity, superoxide dismutase and catalase, a reduction in malondialdehyde concentrations is also expected, thus indicating an improvement in the antioxidant capacity in procedures with beetroot juice ingestion in relation to groups without beetroot juice ingestion, considering a significance level of p< 0.05;It is expected that individuals with polymorphism of the PPARa and ACE genes present different hypotensive responses than individuals without polymorphism of these genes, after an exercise session with ingestion of beetroot juice; adopting a significance level of p<0.05 | — |
Countries
Brazil
Contacts
Public ContactCOMITÊ EM PESQUISA
Outcome results
None listed