COVID-19
Conditions
Interventions
A sample of 94 patients, 47 per group, was calculated considering a 95% confidence power with a margin of error of 5%, and a minimum effect size of significance of 0.3. The chosen effect size was base
Sponsors
Universidade Federal da Bahia
Universidade Federal da Bahia
Eligibility
Inclusion criteria
Inclusion criteria: Patients of both sexes; aged from eighteen to sixty-five years old; with post covid syndrome19; with previous diagnosis of SARS CoV 2 infection by positive reverve transcription polymerase chain reaction for SARS-CoV-2 in combined nasopharyngeal swab molecular test examination of nasal and pharyngeal swab specimens or diagnosis according to computed tomography evidence from at least four weeks prior to admission to the post covid center; medical clearance to exercise
Exclusion criteria
Exclusion criteria: Orthopedic, neurological, or muscular limitations that prevent the adequate performance of physical exercise; Report of angina or previous coronary disease; Uncontrolled hypertension; Heart failure; Previous uncompensated pulmonary disease; Significant aortic stenosis; Active pericarditis or myocarditis; Uncontrolled atrial or ventricular arrhythmias; Third degree atrioventricular (AV) block without pacemaker; Patients who have had radiotherapy and/or chemotherapy in the last 6 months; Signs of embolism or acute thrombophlebitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: the quality of life indicators, as expected to improve after the intervention, will be measured by applying the "EuroQol". The EuroQol is a self-completion classification system that describes health in 5 dimensions: Mobility; Personal care; Habitual activities; Pain or discomfort; Anxiety or depression. Each of these dimensions presents three possibilities of severity, classified as: no problems (level 1), some problems (level 2), and extreme problems (level 3) experienced or felt by the individual. Thus, for each individual, the result of this description is represented by a five digit number. In addition to this descriptive system, the evaluated individual should record the assessment of his or her general health status on a visual analog scale from 0 (worst imaginable health status) to 100 (best imaginable health status) often called the EQVAS thermometer. ;Expected outcome 2: functionality will be assessed using the Patient self report methods for the post covid 19 functional status (PCFS) scale. This is a scale used as an additional outcome measure to assess the final consequences of COVID 19 on functional status. The scale has grades from 0 to 4 and its application consists of an algorithm with 4 simple and objective questions to be answered with "YES" or "NO". After the intervention it is expected that patients will reach higher grades when compared to the baseline values. | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 8: the 6 minute walk test is also a submaximal test that evaluates the aerobic capacity of an individual and will be used. However, this assessment provides other information such as distance walked over 6 minutes and average walking speed. At the end of the test the distance walked should be measured and compared with the reference values according to the study by Iwama et al.;Expected outcome 9: used for the assessment of aerobic capacity, the Chester Step Test (CDT) is a multi stage submaximal test where heart rate and effort levels are continuously monitored. The test will be stopped when the study participant reaches approximately 80% percent of the maximum heart rate, estimated to be 220 minus the subject's age. The patient or physical therapist may also stop the test due to symptoms of dyspnea, fatigue, or both (= slightly tiring), when the patient is unable to maintain the required pace at each stage; when the SpO2 is = 84% percent, or some combination thereof. After the end of the test, the patient's indirect VO2 max will be predicted by means of a normogram specific for the 15-cm TDC. In this normogram, a line is drawn from resting HR to maximum HR through the HR values obtained during the test. A second line is drawn perpendicular to where the initial line and the maximum HR line meet. This second line perpendicular to the first will indicate at the bottom of the normogram in question. The normogram itself provides reference values to be categorized into "excellent"; "good"; "average"; "below average" and "poor" according to the gender and age of the volunteer. ;Expected outcome 10: the cardiopulmonary exercise test will be used and consists of a test capable of evaluating the dynamic cardiovascular, respiratory, and metabolic responses of the individual during exercise. It can be performed on a treadmill or cycle ergometer, with continuous hemodynamic, electrocardiographic, and ventilatory monitoring with the aid of a face mask connecte | — |
Countries
Brazil
Contacts
Public ContactVinicius Gomes
Universidade Federal da Bahia
Outcome results
None listed