Pathological conditions, signs and symptoms
Conditions
Interventions
All patients will be submitted to a clinical and radiographic examination and anamnesis and a initial CBCT analysis will be performed in order to calculate periapical volume in mm³
the endodontic treatment will be performed in a single session (10 patients) and multiple sessions (10 patients) - with application of intracanal medication based on Calcium Hydroxide + physiological
instrumentation and cleaning of the root canals with reciprocating limes (Reciproc R40 and 2.5% sodium hypochlorite will be performed in all groups and root canal will be filled by the single cone te
at the end of the treatment restorations of the teeth treated will de executed with composite resin, a one year control will be done after one year (clinical, radiographic, and tomographic) in order t
Device
Sponsors
ICT Instituto de Ciência e Tecnologia - Unesp de São José dos Campos
Universidade Federal de São Paulo
Eligibility
Age
18 Years to 100 Years
Inclusion criteria
Inclusion criteria: Older than 18 years; Rhinosinusitis without polyps or rhinosinusitis with polyps, according to the EPOS 2012 research criteria; Never submitted to nasal or nasosinusal surgery; Indication of surgical treatment due to failure to initial routine clinical treatment.
Exclusion criteria
Exclusion criteria: Inability to answer the questionnaires; Pregnant or lactating women; Absolute contraindication to the use of corticosteroids; Previous diagnosis of immunodeficiencies; Previous diagnosis of nasosinusal neoplasms; Previous diagnosis of primary ciliary dyskinesias; Previous diagnosis of cystic fibrosis; Use, in the 30 days prior to the inclusion in the study, of oral, intramuscular or intravenous corticosteroids.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| More marked improvement in the level of disease control (assessed according to EPOS 2020), parameters in a quality of life questionnaire (SNOT-22) and specific physical examination (nasal endoscopy using the Lund-Kennedy score) in patients who used nasal irrigation with corticosteroids compared to patients who used nasal spray with corticosteroids. | — |
Secondary
| Measure | Time frame |
|---|---|
| Decrease in the number of exacerbations of Chronic Rhinosinusitis and postponing nasosinusal surgery in patients who used nasal irrigation with corticosteroids compared to patients who used nasal spray with corticosteroids. | — |
Countries
Brazil
Contacts
Public ContactCassia;Gabriela Toia;Matsumoto
ICT Instituto de Ciência e Tecnologia - Unesp de São José dos Campos;Universidade Federal de São Paulo
Outcome results
None listed