Analysis of Salivary Constituents of Elderly Patients with Gingivitis After Use of Dentifrice Incorporated with Brazilian Red Propolis

Analysis of Salivary Biomarkers in Elderly Patients with Gingivitis After Use of 1% Brazilian Red Propolis Based Dentifrice: A Randomized Clinical Trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

REBEC

Registry ID

RBR-5t258m

Enrollment

Unknown

Registered

2020-07-09

Start date

2020-09-01

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gingival diseases

Interventions

In the present study, 80 elderly participants with gingivitis will be selected, will receive removal of the dental biofilm and will be randomized into four groups through the excel program. Group 1 wi

Other

E06.761.726.794

D25.376

Eligibility

Age

66 Years to 100 Years

Inclusion criteria

Inclusion criteria: Healthy volunteers; both genders; presence of gingivitis; age over 65 years; presence of at least five dental elements.

Exclusion criteria

Exclusion criteria: Smoking volunteers; history of alcohol or drug abuse, presence of cognitive problems; dependency on caregiver for daily activities; professional application of fluoridated products in the last 3 months; diagnoses of cardiac, renal, gastrointestinal, hepatic, pulmonary, neurological, psychiatric, hematological or metabolic pathologies.

Design outcomes

Primary

Measure	Time frame
It is expected that the use of red propolis dentifrice associated with fluoride will demonstrate a clinical efficacy superior to fluoridated dentifrice and similar to Parodontax and Periogard.	—

Secondary

Measure	Time frame
Secondary outcomes are not expected.	—

Countries

Brazil

Contacts

Public ContactMara Lotif

Universidade Federal do Ceará

mara_lotif@hotmail.com+55085997339834

Outcome results

None listed

Source: REBEC (via WHO ICTRP)