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Comparative study between endoscopic and conventional surgery for lumbar disc herniation

Randomized trial comparing endoscopic microdiscectomy and conventional open microdiscectomy for the treatment of radiculopathy due to lumbar disc herniations

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5symrd
Enrollment
Unknown
Registered
2018-10-02
Start date
2014-01-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sciatica Lumbar and other intervertebral disc disorders with radiculopathy

Interventions

44 patients with sciatic pain due to a lumbar disc herniation and no improvement after conservative treatment will be divided in 2 groups of 22 patients. One group will be treated with an endoscopic p
Procedure/surgery
M51.1
C05.116.900.307

Sponsors

Instituto de Ortopedia e Traumatologia do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo
Lead Sponsor
Faculdade de Medicina da Universidade de São Paulo
Collaborator

Eligibility

Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Radiating pain to lower limbs. Lumbar disc herniation with nerve compression observed in MRI. Clinical symptoms concordant with MRI images. Six weeks of conservative treatment without significant improvement. Both men and women are included.

Exclusion criteria

Exclusion criteria: Motor weakness grade III or less attributed to nerve compression. High migrated disc herniation. Previous lumbar surgery on the same level. Doble compression on the nerve root. Loss of disc high grater than 50%. Any other surgery contraindication

Design outcomes

Primary

MeasureTime frame
Pain variation between the groups before and 30 days after the intervention measured with the Visual Analog Scale (VAS). We assumed 20 points as a difference and also 20 points as a standard deviation. ;Disability variation before and 30 days after the intervention measured with the Oswestry Disability Index.—

Secondary

MeasureTime frame
recurrence of symptoms due to recurrence herniation during 12 months after the intervention. ;Pain variation between the groups before and one week, 1, 3, 6, 12 months after the intervention measured with the Visual Analog Scale. ;New surgery on the same level of the index procedure 12 months after the intervention. ;Complications. New unwanted events related to the intervention during 12 months.—

Countries

Brazil

Contacts

Public ContactGuilherme Meyer

Instituto de Ortopedia e Traumatologia do Hospital das Clinicas da Faculdade de Medicina da Universidade de São Paulo

gpcmeyer@gmail.com5511941878350

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 19, 2026