Neuromuscular Manifestations
Conditions
Interventions
The present study is structured from the existing guidelines for crossover, randomized and double-blind clinical trials. The allocation of study volunteers will be done randomly by one of the research
E02.190.599.750.750
Sponsors
Universidade Federal do ABC
Universidade Federal do ABC
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
Eligibility
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: Healthy male and female volunteers aged between 18 and 50 years who agree to sign the informed consent form and who meet the criteria listed below will be included. Do not make regular use of psychoactive substances and or with diagnosed psychopathies; They do not have body deformities, stiffness, degenerative changes, osteoarthritis, rheumatoid arthritis and/or related pathologies; Have no history of orthopedic surgery on the trunk or axial segments of the limbs; Do not have contraindications for the use of Transcranial Magnetic Stimulation such as the presence of metals in the skull or implanted devices, history of epilepsy, pregnancy, use of drugs that may interfere with cortical electrical activity such as anticonvulsants, antidepressants and antipsychotics and complications with exposure to magnetic fields ; They do not have metallic implants in the skull, metallic wires implanted in the stimulation region, cochlear implants and pacemakers; They are not incapable of understanding the content of the assessment tools used; Do not present any other situation that the researchers consider as a limiting factor for the study
Exclusion criteria
Exclusion criteria: Volunteers who present any discomfort, psychological or physical, will be excluded from the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate cortical excitability through transcranial magnetic stimulation through the amplitude of the motor evoked potential to verify if there is a modulation of this during the experimental intervention compared to the control intervention at a significance level of 5% pre and post intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the possible correlation between the presence of involuntary movement and the possible corticomotor modulation verified by the amplitude of the evoked potential by transcranial magnetic stimulation; Evaluate the possible autonomic modulation verified by Heart rate variability in its high and low frequency components, in addition to the vagal sympathetic balance; Check the possible association of data collected through transcranial magnetic stimulation, heart rate variability and involuntary movement with the following population variables: age, sex, history of physical activity and perceived stress | — |
Countries
Brazil
Contacts
Public ContactJulia Greve
Hospital das Clínicas da Faculdade de Medicina da USP
Outcome results
None listed