Tobacco Use Disorder
Conditions
Interventions
Twenty-nine participants were blindly randomized to receive one of two experimental interventions consisting of different essential oils, administered by self-application using roll-on devices for a p
Sponsors
Escola de Enfermagem da Universidade Federal de Minas Gerais
Hospital das Clínicas da Universidade Federal de Minas Gerais
Eligibility
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Workers aged 18 years or older; of both sexes and different genders; who reported daily tobacco consumption for at least one year and who voluntarily agreed to participate in the study by providing written informed consent
Exclusion criteria
Exclusion criteria: Exclusion criteria comprised concurrent participation in another smoking cessation treatment; pregnancy; participants who entered medical leave or vacation during the study period and individuals with a diagnosis of asthma or severe allergic rhinitis
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Expected outcome 1: A reduction in nicotine dependence was expected, assessed using the Fagerström Test for Nicotine Dependence, based on comparison of scores obtained in the pre- and post-intervention periods. Changes in nicotine dependence were analyzed using the Wilcoxon test for between-group comparisons. A significance level of 5% and a 95% confidence interval were adopted for all analyses;Observed outcome 1: When the sample was stratified according to the primary outcome, the Angelica archangelica group (A2000) presented a baseline mean score of 5.38 (standard deviation ±1.93) on the Fagerström Test for Nicotine Dependence, which decreased to 4.08 (standard deviation ±2.46) after the intervention, with a statistically significant difference (p=0.027). Similarly, the Piper nigrum group (A2700) showed a baseline mean score of 4.31 (standard deviation ±2.46), which decreased to 2.69 (standard deviation ±2.57) in the post-intervention assessment, also demonstrating a statistically significant difference (p=0.02). No statistically significant differences were observed between groups regarding baseline and final Fagerström scores (p>0.151). In addition, a reduction in Fagerström scores was observed at the end of the intervention period in both groups, with the median decreasing from 5 to 2.5 in the Piper nigrum group and from 6 to 3 in the Angelica archangelica group. Intragroup comparisons indicated a trend toward reduced nicotine dependence following the intervention | — |
Secondary
| Measure | Time frame |
|---|---|
| Expected outcome 2: A reduction in cigarette consumption was expected, assessed by evaluation of tobacco smoking load through comparison between the pre- and post-intervention periods. Changes in tobacco consumption over the course of the study were analyzed using the Wilcoxon test for between-group comparisons. A significance level of 5% and a 95% confidence interval were adopted for all analyses;Outcome found 2: A decrease in smoking load was observed in both groups after the essential oil intervention. At baseline, the Angelica archangelica group presented a median smoking load of 17.40 pack-years, classified as moderate smokers, whereas the Piper nigrum group presented a median of 10 pack-years, classified as light smokers. After the intervention, the median smoking load decreased to 10.5 pack-years in the Angelica archangelica group and to 5.47 pack-years in the Piper nigrum group, with statistically significant intragroup reductions in both groups (p<0.05). No statistically significant difference was observed between groups regarding final smoking load values (p=0.219) | — |
Countries
BR
Contacts
Public ContactVanessa Almeida
Escola de Enfermagem da Universidade Federal de Minas Gerais
Outcome results
None listed