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Effects of sweeteners on the blood glucose and food intake

Effects of high-intensity sweeteners on glycemic response and their acute impact on food intake

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5ss7g7
Enrollment
Unknown
Registered
2018-02-05
Start date
2016-09-15
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity

Interventions

There was be six volunteers in total, each subject received five different beverages, randomly. Each test day, the volunteers drinked one of the beverages: 1) sucrose beverage (SAC)
2) aspartame beverage (ASP)
sucralose beverage (SUC)
Stevia beverage (STV) and
5) non-sweetened beverage (NA). Between the beverages there was be at least a free interval of 1 day. The application sequence was be given by lot. All volunteers received the five beverages.
Dietary supplement
SP6.051.227

Sponsors

Universidade Federal de Viçosa
Lead Sponsor
Universidade Federal de Viçosa
Collaborator

Eligibility

Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: Eligibility criteria included adult (20-40 years old), eutrophic (BMI ranging from 18.5 and 24.9 kg /m2), with adequate body fat percentage (women: 20 to 30% and men: 12 to 20%), non-consumers of sweeteners and/or diet and light products (at least once a week), no smoking habits, not be pregnant or lactating and no family history of diabetes or glucose intolerance, no allergy or aversion to food tested in the study, no use of drugs that affect glycaemia or appetite, stable weight (change < 3 kg in the last 3 months) and not on a weight loss diet.

Exclusion criteria

Exclusion criteria: Individuals outside the specified age group and body composition, smokers, pregnant or lactating women; with glycemic changes or a family history of diabetes or glucose intolerance; users of drugs that affect glycaemia or appetite, individuals with weight instability or on a weight loss diet, as well as all volunteers who express an interest in withdrawing from the study.

Design outcomes

Primary

MeasureTime frame
Expected outcome: Lower food intake (p<0,05), evaluated through food registration, with the consumption of beverages sweeteneds with aspartame, stevia and sucralose, in relation with beverages non-sweetened and sweetened with sucrose. Outcome found:Food intake did not differ between groups.

Secondary

MeasureTime frame
Expected outcome: Lower glycemic response area under the curve (p<0,05) with the consumption of beverages sweeteneds with aspartame, stevia and sucralose, in relation with beverages non-sweetened and sweetened with sucrose. Outcome found: Higher glycemic response area under the curve (p<0,05) with the consumption of beverages sweeteneds with stevia in relation with beverage sweetened with sucrose. No difference was observed between the other beverages.

Countries

Brazil

Contacts

Public ContactAdriane Machado

Universidade Federal de Viçosa

adriane_nutricao@hotmail.com+55-031-3899-4193

Outcome results

None listed

Source: REBEC (via WHO ICTRP)