Autism Spectrum Disorder
Conditions
Interventions
This is a randomized controlled clinical trial conducted in children with Autism Spectrum Disorder, in which 150 participants are randomly allocated in a 1:1:1 ratio into three parallel groups. Group
Sponsors
Instituto de Ensino e Pesquisa Alberto Santos Dumont
Instituto Internacional de Neurociências Edmond e Lily Safra (IINELS)
Eligibility
Age
3 Years to 12 Years
Inclusion criteria
Inclusion criteria: Participants of both sexes; diagnosis of Autism Spectrum Disorder confirmed by a professional not affiliated with the research team; age between 3 and 12 years; availability of a finalized diagnostic report confirming Autism Spectrum Disorder prior to the beginning of the evaluations; written informed consent provided by parents or legal guardians
Exclusion criteria
Exclusion criteria: Absence of a confirmed Autism Spectrum Disorder diagnosis or diagnostic report; use of pacemakers or other electronic implants including cochlear implants; presence of metal implants or plates in the skull or body; history of epilepsy or seizures; neurological comorbidities such as brain tumors or intracranial infections; history of brain surgery; severe cardiac disease
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Reduction of cerebral hyperactivity measured by electroencephalography in children with autism spectrum disorder after transcranial electrical stimulation including transcranial direct current stimulation or transcranial random noise stimulation with comparison between baseline measurements collected before the intervention and measurements collected after the intervention period | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in behavioral and communication outcomes including reduction of hyperactivity and repetitive behaviors increase in attention and social interaction improvement in speech evaluation of visual preference for facial expressions using eye tracking analysis of sociodemographic characteristics and assessment of behavioral patterns and maintenance of effects up to eight months after transcranial electrical stimulation | — |
Countries
Brazil
Contacts
Public ContactAnna Karoline Almeida Soares
University of South Florida
Outcome results
None listed