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Non-invasive brain stimulation in neurological conditions

Non-invasive neuromodulation in neurological clinical conditions

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5s76ksq
Enrollment
Unknown
Registered
2025-10-13
Start date
2025-11-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nervous System Diseases

Interventions

This is a blinded, case-control, umbrella intervention clinical study to be conducted at the Neurorehabilitation and Neuromodulation Laboratory of the Interprofessional Health School Clinic (CEIS) at
E02.621.820
E02.331.900

Sponsors

Universidade Federal do Espírito Santo
Lead Sponsor
Universidade Federal do Espírito Santo
Collaborator

Eligibility

Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Participants aged 18 years or older; of both sexes; who provide written informed consent will be included; eligibility requires a functional diagnosis of communication disorders or stomatognathic dysfunctions of neurological etiology (dysphagia, dysphonia/dysarthrophonia, aphasia, or somatosensory tinnitus); a functional diagnosis of gait and balance disorders; chronic pain; and/or a sympathetic or parasympathetic index outside the normal range (–1 to 1) in heart rate variability, observed in at least two of the three measurements of the orthostatic test

Exclusion criteria

Exclusion criteria: Participants who do not use the Portuguese oral language; who have rheumatological diseases such as rheumatoid arthritis and ankylosing spondylitis; with cardiac arrhythmia or other cardiovascular conditions using beta-blockers; pregnant women or women in the puerperium or postpartum period; patients diagnosed with cancer and severe osteoporosis; who have absolute contraindications for non-invasive brain stimulation (pacemaker, epilepsy, cochlear implant)

Design outcomes

Primary

MeasureTime frame
Faster and safer remission or attenuation of human communication disorders, stomatognathic functions, chronic pain, and motor and non-motor functional alterations through the application of non-invasive brain stimulation than through conventional therapeutic procedures—

Secondary

MeasureTime frame
Change in overall human communication disorders, stomatognathic functions, chronic pain, and motor and non-motor functional alterations activity in daily life—

Countries

Brazil

Contacts

Public ContactCarolina Comarela

Universidade Federal do Espírito Santo

cfanhoque@gmail.com+5527992587245

Outcome results

None listed

Source: REBEC (via WHO ICTRP)