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Study of the application of protocol in the prevention of peri-intraventricular haemorragia in preterm newborns

Study of the Application of a bundle in the prevention of peri-intraventricular haemorragia in preterm newborns

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5s4yqh
Enrollment
Unknown
Registered
2019-10-16
Start date
2016-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Peri-intraventricular hemorrhage in preterm newborns

Interventions

Application of a bundle for 132 preterm infants born weight less or equal 1,500 g and or gestational age less or equal 34 weeks during six-month period.
Other

Sponsors

Universidade Estadual do Ceará
Lead Sponsor
Maternidade Escola Assis Chateubriant
Collaborator

Eligibility

Age
24 Weeks to 34 Weeks

Inclusion criteria

Inclusion criteria: To be premature with gestational age less than or equal to thirty-four (34) weeks at birth and / or Birth weight less than or equal to 1,500 (one thousand, five hundred) grams.

Exclusion criteria

Exclusion criteria: Newborns with congenital malformations, genetic syndromes and those with congenital infections of the TORCHS group (syphilis, rubella, herpes, toxoplasmosis and cytomegalovirus). Newborns who died before the first ultrasonographic examination or were transferred to another institution due to overcrowding of the Neonatal Unit.

Design outcomes

Primary

MeasureTime frame
Peri-Intraventricular Hemorrhage (IVHD) in Newborns;The intervention is expected to decrease rates of peri-intraventricular hemorrhage (IVH) in the unit's newborns.

Secondary

MeasureTime frame
Improvement of the degree of peri-intraventricular hemorrhage (IVH) in newborns. ;After application of the bundle, there was a reduction in the incidence of HPIV in 41.4% and 32.4% in severe forms (degrees III and IV). The rate of HPIV and the classification of bleeding was verified in the infants who were hospitalized during the previous year of the intervention in the unit. After intervention (bundle use), the decrease in the rates of HPIV from 90% to 63% was verified in infants who were born weighing less than 1500 grams and with less than 34 weeks. In addition, prior to intervention, infants who were born premature and underweight, only 10% did not present bleeding; after intervention, 63% of these infants did not experience any type of hemorrhage. The presence of HPIV was evaluated using the transfontanel ultrasound (USTF), which is the diagnostic imaging method of choice for the diagnosis of peri-intraventricular hemorrhage, due to its practicality, safety, precision, and low cost. All preterm infants underwent transfontanel ultrasound with 3 (three) to 5 (five) days of life and thereafter every 15 (fifteen) days.

Countries

Brazil

Contacts

Public ContactRhanna Carvalho

Universidade Estadual do Ceará

rhannalima@gmail.com55-085-31019612

Outcome results

None listed

Source: REBEC (via WHO ICTRP)