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Immediate and adaptive effect of interventions with and without physical exercise on the quality of walking in people with Parkinson's disease

Acute and chronic effect of motor and non-motor intervention on gait asymmetry in patients with Parkinson's disease

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5s234bn
Enrollment
Unknown
Registered
2024-05-28
Start date
2024-08-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Parkinson's disease

Interventions

This is an “umbrella” research project that includes three different interventions, which will be carried out sequentially as the result of the next intervention is dependent on the previous one. Cont
E01.370.350.578.875.500

Sponsors

Universidade Estadual Paulista Júlio de Mesquita Filho
Lead Sponsor
Universidade Estadual Paulista Júlio de Mesquita Filho
Collaborator

Eligibility

Age
50 Years to 80 Years

Inclusion criteria

Inclusion criteria: For participants of the Parkinson group: have a minimum age of 50 and a maximum of 80 years; both genders; having a diagnosis by a private neurologist that indicates the presence of Idiopathic Parkinson Disease; have independent locomotion without the aid of auxiliary devices (cane, for example); being under drug treatment with stable levodopa for at least 3 weeks; not having undergone brain surgery or deep brain stimulation for Parkinson Disease treatment; no history of orthopedic and vision problems that make it impossible to comply with the experimental protocol (corrected vision with glasses is allowed); not having uncontrolled cardiovascular, metabolic or inflammatory problems; not showing advanced cognitive decline; present a medical certificate authorizing the performance of physical exercise. For control group participants: have a minimum age of 50 and a maximum of 80 years; both genders; independent locomotion without aid of auxiliary devices; not having history of orthopedic and vision problems that make it impossible to comply with the experimental protocol (corrected vision with glasses is allowed); not having uncontrolled cardiovascular, metabolic or inflammatory problems; not showing advanced cognitive decline

Exclusion criteria

Exclusion criteria: Do not present proof of Parkinson's disease, only for participants in the Parkinson's group in interventions 1 and 3; those with other neurological disorders; heart problems (i.e., arrhythmias, indication of myocardial ischemia); musculoskeletal disorders; cognitive deficits; brain surgery or Deep Brain Stimulation for the treatment of Parkinson disease

Design outcomes

Primary

MeasureTime frame
To compare the effect of a physical exercise protocol focusing on the side most affected by Parkinson's disease versus the less affected side versus both sides on gait asymmetry in people with Parkinson's disease;To compare the effect of a physical exercise protocol focused on the lower limbs performed in conjunction with an intermittent normobaric hypoxia procedure on gait asymmetry in people with Parkinson's disease;Verify the effects of a 12-week intervention protocol on gait asymmetry in people with Parkinson's disease

Secondary

MeasureTime frame
Determine neural, blood and motor factors associated with gait asymmetry so that specific strategies can be proposed for the rehabilitation of gait asymmetry in people with Parkinson's disease

Countries

Brazil

Contacts

Public ContactJônatas Augusto Cursiol

Universidade Estadual Paulista Júlio de Mesquita Filho

jonatas.cursiol@unesp.br+55(14)31039438

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 4, 2026