Keloid
Conditions
Interventions
All patients included will first be evaluated by anamnesis and clinical examination regarding the characteristics of their skin and keloid. Next, they will answer specific questionnaires to complement
Sponsors
Universidade Federal de São Paulo - Unifesp
Universidade Federal de São Paulo - Unifesp
Eligibility
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: We will include patients between the ages of 18 and 50; of both sexes; with keloids on the anterior thoracic region; without specific treatment in the last six months; and with at least 12 months of evolution
Exclusion criteria
Exclusion criteria: Patients with more than one keloid in the anterior thoracic region; with specific treatment for less than six months; patients with collagen diseases; malignant neoplasms of any etiology; current topical or systemic use of corticosteroids and chemotherapy; pregnant and lactating women; patients who do not complete any of the stages proposed by the present study; patients who willingly withdraw their voluntary participation, without any prejudice to their treatment and medical follow-up, will not be included
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| It is expected to find improvement in the clinical signs and symptoms of keloid, such as pain, itching, scar hyperemia, consistency, flexibility, pliability, thickness, and coloration, verified by lipografting, ascertained by specific clinical examination of the keloid and specific questionnaires for evaluating the pathological scar, with a variation of at least 5% between pre- and post-intervention measurements. | — |
Secondary
| Measure | Time frame |
|---|---|
| It is expected to find improvement in the quality of life of patients with keloids, verified through lipografting, ascertained through specific quality of life evaluation questionnaires, with a variation of at least 5% between pre- and post-intervention measurements.;It is expected to find morphological and functional improvements in keloid tissue, verified by lipografting, from the findings by histomorphometric and immunohistochemical analysis, with a variation of at least 5% between pre- and post-intervention measurements. | — |
Countries
Brazil
Contacts
Public ContactFelipe Isoldi
Universidade Federal de São Paulo - Unifesp
Outcome results
None listed