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Effects of intensities of exercise combined on type 2 diabetic women in menopause

Effects of exercise intensity on metabolic, respiratory and cardiovascular parameters in type 2 diabetic women - a clinical randomized trial - T2DM: Type 2 Diabetes Mellitus

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5rb2ps
Enrollment
Unknown
Registered
2020-01-07
Start date
2018-05-01
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 Diabetic Women in Menopause

Interventions

The study was conducted with 16 postmenopausal women aged 47 to 65 years and with type 2 diabetes mellitus. Anthropometric data, body composition, cardiovascular data, biochemical analyzes, quality of
Behavioural
G11.427.410.698.277
E05.318.308.980

Sponsors

Universidade Federal de Lavras
Lead Sponsor
Financiamento Próprio
Collaborator

Eligibility

Sex/Gender
Female
Age
40 Years to 70 Years

Inclusion criteria

Inclusion criteria: Being a carrier of DM2; being in amenorrhea for at least 12 consecutive months; be able to exercise by Par-Q; being sedentary or not engaging in regular physical activity (not practicing a minimum of 150 minutes of physical exercise per week according to WHO criteria).

Exclusion criteria

Exclusion criteria: Use of hormone replacement therapy; smoking; presence of coronary artery disease or debilitating diseases; hysterectomized women.

Design outcomes

Primary

MeasureTime frame
Of the 16 women who completed the study, 10 had physical activity in MI and 6 in AI. The average age in group AI was 57.8 ± 1.6 years and in MI 58.2 ± 1.4 years. The average time of menopause in years was 6.9 ± 0.8 in MI and 7.7 ± 2.0 in AI. The participants' quality of life was assessed by applying the SF-36 questionnaire before and after physical training. Although there was an increase in the SF-36 score in all domains in both groups after physical exercise, only in the MI group and in the functional capacity, pain and mental health domains there was a significant improvement (p?0.05). The Blood pressure levels, biochemical parameters and HR before training began were similar between groups AI and MI (p?0.05). SBP, DBP and MBP decreased in both groups after physical training (p?0.05). There was also improvement in glycemic control after the end of the study, verified by the reduction in glycated hemoglobin in both groups (p?0.05). Regarding the lipid profile, the changes induced by physical training were influenced by the intensity of the exercise. HDL-c increased after exercise only in group AI and HDL-c delta (HDL-c after exercise - baseline HDL-c) also had statistical significance (p?0.05) only in this group. GADs were more likely to improve in group AI, but no significant difference was observed (significance level of 95%). However, analyzing the delta values ??(TAG after exercises –TAG basal), a significant reduction (p?0.05) was observed only in the AI ??group. Both LDL-c and its delta had a significant reduction (p?0.05) only in the MI group. The other biochemical parameters (TC, GJ, CT / HDL) and HR were not influenced by physical training under the conditions used in this study.

Secondary

MeasureTime frame
Anthropometric data (body weight, BMI, WC) and basal body composition were similar (p?0.05) between the AI and MI groups. Physical training did not change the anthropometric parameters, however, there was an improvement in body composition with increase of lean mass, increase of water% and reduction of fat mass after the end of the physical exercises in both groups (p?0,05). no differences between them.

Countries

Brazil

Contacts

Public ContactPedro Machado

Universidade Federal de Lavras

pedro96gustavo@gmail.com+5535997147338

Outcome results

None listed

Source: REBEC (via WHO ICTRP)