Anxiety and singing: influence of administration of a single dose of Oxytocin in men

Anxiety and singing voice: clinical parameters and effects of acute administration of Oxytocin in men

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

REBEC

Registry ID

RBR-5r5sc5

Enrollment

Unknown

Registered

2017-03-08

Start date

2015-10-20

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Performance anxiety

Interventions

Drug

D27.505.696.277.950.015

The singers will be allocated in two groups: 1. Oxytocin-placebo group (GOP): 25 male singers with three years of experience will appear on two different days with a one-week interval between meeting

Eligibility

Sex/Gender

Male

Age

18 Years to 35 Years

Inclusion criteria

Inclusion criteria: Male singers; Aged between 18 and 35 years; With training or experience in singing voice of at least three years; Perform at least one musical presentation in public.

Exclusion criteria

Exclusion criteria: Use of the following medications; Antihistamine, antidepressants, antihypertensive, hypoglycemic and anti-inflammatory; Complaint of auditory acuity; History of neurological disease, psychiatric disorders, renal, pulmonary, hepatic and / or cardiovascular problems; Abuse of alcohol, tobacco and users of illicit substances; Moderate to severe dysphonia.

Design outcomes

Primary

Measure	Time frame
Check that the acute intranasal administration of oxytocin in men singers are able to minimize the effects of anxiety in musical performance in vocal quality . Through analysis of the vocal acoustic measures of voice recording of individuals throughout the research , using the pitch Real time software (Figure 2) Hardware Computerized Speech Lab / Model 6103 Kay Pentax® and MultiDimensional Voice Program ( MDVP ) of Computerized software speech Lab / Model 6103 Kay Pentax® and perceptual evaluation and intraobserver visual and inter vocal quality and musical performance in the singing voice recordings in audio and video.;Check that the acute intranasal administration of oxytocin in men singers are able to minimize the effects of anxiety in musical performance in self-perception during the singing. through analysis of responses throughout the experiment obtained by : Analog Scale of Humor - VAMS Scale for self-assessment of performance in public - state version ( SSPS -E ) and scale perceptual self-assessment and touch kinesthetic voice of individuals of oxytocin - placebo groups (GOP ) , for which it was administered intranasal oxytocin at first and placebo in the second time ; B). Group called placebo - oxytocin ( GPO) for which will be administered placebo and subsequently oxytocin.	—

Measure

Time frame

Check that the acute intranasal administration of oxytocin in men singers are able to minimize the effects of anxiety in musical performance in vocal quality . Through analysis of the vocal acoustic measures of voice recording of individuals throughout the research , using the pitch Real time software (Figure 2) Hardware Computerized Speech Lab / Model 6103 Kay Pentax® and MultiDimensional Voice Program ( MDVP ) of Computerized software speech Lab / Model 6103 Kay Pentax® and perceptual evaluation and intraobserver visual and inter vocal quality and musical performance in the singing voice recordings in audio and video.;Check that the acute intranasal administration of oxytocin in men singers are able to minimize the effects of anxiety in musical performance in self-perception during the singing. through analysis of responses throughout the experiment obtained by : Analog Scale of Humor - VAMS Scale for self-assessment of performance in public - state version ( SSPS -E ) and scale perceptual self-assessment and touch kinesthetic voice of individuals of oxytocin - placebo groups (GOP ) , for which it was administered intranasal oxytocin at first and placebo in the second time ; B). Group called placebo - oxytocin ( GPO) for which will be administered placebo and subsequently oxytocin.

—

Secondary

Measure	Time frame
Identify the differences in voice quality between classical and popular singers in anxiety situation that participate in the research, through acoustic analysis of the vocal measures voice recording of individuals MultiDimensional Voice Program ( MDVP ) of Computerized Speech Lab software / model 6103 of Kay Pentax® .	—

Countries

Brazil

Contacts

Public ContactFlávia;Lilian de Lima Osório ;Neto Aguiar-Ricz

Faculdade de Medicina de Ribeirão Preto - Universidade de São Paulo;Faculdade de Medicina de Ribeirão Preto - Universidade de São Paulo

flaliosorio@ig.com.br;liricz@fmrp.usp.br+55(16)36022703;+55(16)33150592

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Feb 11, 2026