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Effects of an Exercise Program on the Cardiovascular System and Physical Endurance of Chronic Renal patients undergoing hemodialysis.

Effects of a Resistance Exercise Program on the Autonomic Cardiovascular Function and without Physical Conditioning of Chronic Renal patients under hemodialysis treatment

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5ndvwr
Enrollment
Unknown
Registered
2018-11-09
Start date
2018-11-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Renal Insufficiency. renal dialysis

Interventions

Patients will be randomly divided into experimental group and control group, where all will be submitted to an initial evaluation that will consist of anamnesis and questionnaires referring to osteomu
Other
H02.010.625

Sponsors

Hospital Universitário da Universidade Federal do Maranhão
Lead Sponsor
Clínica de Rim e Hipertensão Arterial
Collaborator

Eligibility

Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Age greater than 18 years; both genders; undergoing hemodialysis for more than 3 months; who have the cognitive ability to understand the research process and sign the informed consent form; volunteer to participate in the study.

Exclusion criteria

Exclusion criteria: Patients with diseases or some type of musculoskeletal disability; bone or joint disorders that make evaluations and exercise protocol impossible; dialysis by catheter in the femoral artery or catheter in the jugular vein; neurological and behavioral changes that in some way render the protocol inapplicable; patients with severe cardiovascular disease; patients presenting hematocrit less than or equal to 30% and / or hemoglobin less than or equal to 10g / D; patients with untreated mitral or aortic insufficiency / stenosis; severe pulmonary conditions; pathologies that incapacitate the study (amputation of upper limbs or lower limbs, amaurosis, deep venous thrombosis); patients who already had resistance exercise.

Design outcomes

Primary

MeasureTime frame
The expected outcome is improved neural control of cardiac function with increased heart rate variability. It was verified by performing the 12-lead electrocardiogram for 10 minutes at rest and measured by index calculation based on statistical operations of the R-R intervals (time domain) and by the spectral analysis of ordered R-R intervals (frequency domain). Comparing the pre-intervention evaluation and after 12 weeks of intervention.;It is also expected as a primary outcome, to verify an improvement in the functional capacity of the chronic renal hemodialytic patient, measured by the 6-minute walk test, aiming to increase the distance covered in the pre-determined time. This will be done in a flat corridor at least 20 meters long, for a period of 6 minutes, where the total distance traveled in meters will be used as the evaluation score. Comparing the pre-intervention evaluation and after 12 weeks of intervention.

Secondary

MeasureTime frame
Improvement of peripheral muscle strength, with an increase in the force value measured in dynamometry, where the palmar grip strength will be verified; asking the subjects to press the dynamometer with the maximum possible force, with the flexion of the fingers, repeating the maneuver three times, considering the best attempt. Comparing the pre-intervention evaluation and after 12 weeks of intervention.;Reduction in anxiety / depression score, if present, measured through the Beck Anxiety and Depression questionnaires and applied in the pre-intervention evaluation and after 12 weeks of intervention.;Increase in sleep quality score assessed by the Pittsburgh Sleep Quality Index and applied in the pre-intervention evaluation and after 12 weeks of intervention.;In order to analyze whether there were changes in uric acid, creatinine, calcium, glucose, insulin, potassium, phosphorus, CRP, albumin, and serum creatinine levels, the results of the laboratory tests were checked before, during and after the end of the exercise program, total cholesterol, hematocrit and hemoglobin.

Countries

Brazil

Contacts

Public ContactEmanuelle Cristinne Sá

Hospital Universitário da Universidade Federal do Maranhão

fisioemanuelle@hotmail.com+55-98-988316697

Outcome results

None listed

Source: REBEC (via WHO ICTRP)