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Effects of Brazilian nut consumption on the expression of factors that regulate inflammation in patients with coronary artery disease

Effects of Brazil nut supplementation (Bertholletia excelsa H.B.K.) in Nrf2 and NFkB expression in coronary arterial disease patients

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5mzzd4
Enrollment
Unknown
Registered
2017-10-17
Start date
2015-06-10
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerosis of aorta

Interventions

Sixty patients with coronary artery disease will be recruited who randomly 30 patients will be in the supplementation group and 30 in the control group. Only the supplementation group will receive 1 u
Dietary supplement
SP6.051.227

Sponsors

Pós-graduação em Ciências Cardiovasculares, Universidade Federal Fluminense
Lead Sponsor
Pós-graduação em Ciências Cardiovasculares, Universidade Federal Fluminense
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Will be included in the study: men and women over 18 and non-smokers.

Exclusion criteria

Exclusion criteria: Patients with autoimmune and infectious diseases, pregnant and lactating women; Cancer and AIDS; Patients taking catabolic drugs and antioxidant vitamin supplements.

Design outcomes

Primary

MeasureTime frame
Increased expression of Nrf2 assessed by rt-PCR in patients with coronary artery disease after 3 months of supplementation with 1 unit of brazil nut—

Secondary

MeasureTime frame
Secondary outcomes are not expected—

Countries

Brazil

Contacts

Public ContactLudmila ;Milena Cardozo;Stockler pinto

Pós-graduação em Ciências Cardiovasculares, Universidade Federal Fluminense;Pós-graduação em Ciências Cardiovasculares, Universidade Federal Fluminense

ludmila.cardozo@gmail.com;milbarcza@gmail.com+55(21)2629 9382 ;+55(21)2629 9382

Outcome results

None listed

Source: REBEC (via WHO ICTRP)