Muscle damage
Conditions
Interventions
Data will be collected from male athletes, aged between 20 and 30 years, from Rugby Caxias club, located in Caxias do Sul, Rio Grande do Sul. This study will have a randomized crossover clinical trial
biochemical markers of muscle injury and inflammation, such as creatine kinase (CK), TGO (glutamic-oxalacetic transaminase) enzyme (interleukin 6 (IL-6) and 10 (IL-10), and tumor necrosis factor alpha
Other
V03.175.250.500.500
Sponsors
Centro Universitário Metodista
Centro Universitário Metodista
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: Male players will be included, aged between 20 and 30 years and at least 1 year play as holders of the rugby team of Caxias do Sul / RS and have daily training routines, between the game itself and physical training.
Exclusion criteria
Exclusion criteria: Injured athletes who are out of training and / or competing in the past six months, athletes using anti-inflammatory drugs, and athletes who have an aversion or allergy to the components of grape juice will be excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome will be the evaluation of oxidative stress parameters (enzymatic activity, lipid peroxidation, protein oxidation, DNA damage, antioxidant activity) before and after grape juice consumption. These parameters are expected to decrease after chronic consumption (14 days) of red grape juice. | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome will be the assessment, before and after the consumption of grape juice, of inflammatory marker parameters and indicators of pain and effort, which may be related to muscle fatigue. Chronic (14 days) consumption of grape juice is expected to decrease inflammatory markers and indicators of pain and effort, as well as favoring the aerobic capacity of the individuals in this study. | — |
Countries
Brazil
Contacts
Public ContactCaroline Dani
Centro Universitário Metodista
Outcome results
None listed