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Effect of a supplement combined with exercise on muscle loss and recovery in older adults

Angiotensin-(1-7): its applications in the management of lean mass loss and muscle recovery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5ky68sc
Enrollment
20
Registered
2026-03-27
Start date
2026-02-23
Completion date
Unknown
Last updated
2026-03-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle atrophy Sarcopenia

Interventions

Controlled, randomized, double blind, crossover clinical trial with two intervention periods, in which participants will be randomly allocated into two conditions, receiving angiotensin 1 7 complexed

Sponsors

Universidade Federal de Ouro Preto
Lead Sponsor
Fundação de Amparo à Pesquisa do Estado de Minas Gerais
Collaborator

Eligibility

Age
65 Years to No maximum

Inclusion criteria

Inclusion criteria: older adults aged 65 years or older residing in the cities of ouro preto and mariana; presenting skeletal muscle loss; presenting any level of sarcopenia including severe sarcopenia; who agree to participate in the proposed intervention

Exclusion criteria

Exclusion criteria: participants who do not meet the inclusion criteria; who refuse to sign the informed consent form; who do not fully complete the research instruments; who do not demonstrate interest in participating in the intervention; individuals with severe liver disease; limiting cardiovascular disorders; severe renal impairment; dementia; parkinson disease; severe neuropsychological disorders

Design outcomes

Primary

MeasureTime frame
It is expected to find improvements in muscle mass, muscle function, and related parameters in older adults with sarcopenia undergoing supplementation with angiotensin 1 7 combined with physical exercise

Secondary

MeasureTime frame
No secondary outcomes are expected

Countries

BR

Contacts

Public ContactLenice Becker

Universidade Federal de Ouro Preto

lenice@ufop.edu.br+553135511960

Outcome results

None listed

Source: REBEC (via WHO ICTRP) · Data processed: Apr 4, 2026