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Effect of tumeric extract supplementation on oxidative stress and inflammation after running

Effect of Curcula longa L. supplementation on oxidative and inflammation markers after endurance exercise

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
REBEC
Registry ID
RBR-5kw3bz
Enrollment
Unknown
Registered
2018-07-16
Start date
2015-08-08
Completion date
Unknown
Last updated
2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Study with healthy humans performing a half marathon race Sports Nutritional Physiological Phenomena

Interventions

Participants ingested 3 opaque capsules per day containing curcuma long l. extract (500 mg each, Supplemented group, 14 athletes) or placebo (cellulose microcrystalline, 500 mg each, Placebo group, 14
Dietary supplement
SP6.051.227
D26.660

Sponsors

Faculdade de Nutrição da Universidade Federal de Goiás
Lead Sponsor
Faculdade de Nutrição da Universidade Federal de Goiás
Collaborator

Eligibility

Sex/Gender
Male
Age
25 Years to 50 Years

Inclusion criteria

Inclusion criteria: Men, eutrophic, aged between 25 and 50 years, amateur runners

Exclusion criteria

Exclusion criteria: Participants on weight loss diet/medication, diagnose with any acute or chronic diseases, taking medication that could affect the immune system, injured, smokers, and with a history of chronic alcoholism.

Design outcomes

Primary

MeasureTime frame
A reduction on myoglobin concentrations with the Curcuma longa L. extract, verified by the Enzyme-Linked Immunosorbent Assays (ELISA) method, based on a variation of at least 5% in pre and post-intervention measurements.;A reduction on creatine kinase activity with the Curcuma longa L. extract, verified by the colorimetric method, based on a variation of at least 5% in pre and post-intervention measurements.

Secondary

MeasureTime frame
A reduction on muscle soreness with the Curcuma longa L. extract, verified by biceps femoris muscle palpation and stretching, based on a variation of at least 5% in pre and post-intervention measurements.;An increase on interleukin-10 concentrations with the Curcuma longa L. extract, verified by the Enzyme-Linked Immunosorbent Assays (ELISA) method, based on a variation of at least 5% in pre and post-intervention measurements.

Countries

Brazil

Contacts

Public ContactFlavia;João Faria ;Mota

Faculdade de Nutrição da Universidade Federal de Goiás;Faculdade de Nutrição da Universidade Federal de Goiás

flaviarasmussen@hotmail.com;jfemota@gmail.com+55 (62) 3209-6270;+55 (62) 3209-6270

Outcome results

None listed

Source: REBEC (via WHO ICTRP)