Impact of physical exercise on periodontal parameters in patients with periodontitis.

Evaluation of the relationship between physical activity and periodontal condition before and after non-surgical periodontal therapy.

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

REBEC

Registry ID

RBR-5jxh6c

Enrollment

Unknown

Registered

2020-04-24

Start date

2019-07-16

Completion date

Unknown

Last updated

2025-10-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Periodontitis

Interventions

Participants will be randomly divided into two groups (each group with 15 participants), all of which will be submitted to both non-surgical periodontal treatment (TPNC) and physical exercises from th

F01.145.632

E06.721.189.350

Eligibility

Age

30 Years to 50 Years

Inclusion criteria

Inclusion criteria: Age between 30 to 50 years; At least 20 teeth, excluding third molars; Negative medical / dental history for antibiotic therapy and use of anti-inflammatory drugs in the last 6 months prior to the study; Negative dental history for non-surgical periodontal therapy in the last 6 months prior to the study; Habits of a sedentary life, therefore not practicing regular physical activities; Patients with a BMI of 18.5 to 29.9 kg / m²; Smartphone compatible with the Seven® application; Diagnosis of Periodontitis.

Exclusion criteria

Exclusion criteria: Smokers; Diabetics; Hypertensive; Presence of systemic diseases that show inflammatory, immune or hormonal changes; Contraindication from health professionals for the practice of physical activities.

Design outcomes

Primary

Measure	Time frame
To evaluate the reduction in clinical inflammation through probing pocket depth (PPD), considering mean PPD reduction (in mm) in pockets equals or greater than 4mm.	—

Secondary

Measure	Time frame
To evaluate clinical attachment gain through clinical attachment level, using full-mouth mean (in mm);To evaluate inflammatory component of the bottom of the pocket using bleeding on probing, considering the percentage of bleeding sites per individual;To evaluate gingival crevicular fluid cytokine expression using Luminex, quantifying chosen proteins and performing intra- and intergroup comparisons;To evaluate microbial count using DNA checkerboard hybridization, quantifying chosen bacteria and performing intra- and intergroup comparisons;To evaluate quality of life through OHIP-14 questionnaire, comparing the results between groups	—

Measure

Time frame

To evaluate clinical attachment gain through clinical attachment level, using full-mouth mean (in mm);To evaluate inflammatory component of the bottom of the pocket using bleeding on probing, considering the percentage of bleeding sites per individual;To evaluate gingival crevicular fluid cytokine expression using Luminex, quantifying chosen proteins and performing intra- and intergroup comparisons;To evaluate microbial count using DNA checkerboard hybridization, quantifying chosen bacteria and performing intra- and intergroup comparisons;To evaluate quality of life through OHIP-14 questionnaire, comparing the results between groups

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Countries

Brazil

Contacts

Public ContactJoão Steffens

Universidade Federal do Paraná

joaopaulosteffens@hotmail.com+55(41)33604134

Outcome results

None listed

Source: REBEC (via WHO ICTRP)