End Stage Liver Disease
Conditions
Interventions
Experimental group: 50 individuals post liver transplantation who will do physical exercise for 8 weeks, 3 times a week, 24 attendances in total. The protocol includes muscle stretching, exercises of
G11.427.590.530.698.277
Q65.060
Sponsors
Hospital Universitário Walter Cantídio
Universidade Federal do Ceará
Eligibility
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Patients of both gender; age between 18 and 70 years; with 1 month post liver transplantation; who present clinical conditions to perform the proposed procedures
Exclusion criteria
Exclusion criteria: Patients with post-transplant liver encephalopathy; cognitive changes that make it difficult to answer the questionnaires; patients who underwent surgical reintervention less than 1 month after the transplant; those who have clinical changes observed in complementary exams; graft rejection; difficulty in walking and orthopedic limitations that make it impossible to carry out the six-minute walk tests and step test and participation in the physical activity program and patients with severe cardiovascular disease who contraindicated exercise
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Significant increase of the functional capacity from the increase of the walked distance in the six-minute walking test after 8 weeks of the intervention protocol. | — |
Secondary
| Measure | Time frame |
|---|---|
| Significant improvement in the quality of life using the quality of life questionnaires (SF-36) after 8 weeks of the intervention protocol. ;Significant decrease in the anxiety and depression score punctuation using the Hospital Anxiety and Depression Scale after 8 weeks of the intervention protocol. ;Significant improvement of respiratory muscle strength using manovacuometry and the maximum strength of upper limb, using the one maximum repetition after 8 weeks of the intervention protocol. ;Significant improvement of fatigue and dyspnea using the fatigue severity scale and the modified dyspnea index (MMRC) and sleep by Pittsburgh Sleep Quality Index (PSQI) after 8 weeks of the intervention protocol. | — |
Countries
Brazil
Contacts
Public ContactClarissa Magalhães
Outcome results
None listed